Results 71 to 80 of about 233,918 (277)

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang   +10 more
wiley   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp   +4 more
wiley   +1 more source

Generalized roughness in (∈,∈∨q)-fuzzy ideals of hemirings

open access: yesKuwait Journal of Science, 2017
Generalized roughness for fuzzy ideals in hemirings is studied. Approximations for fuzzy prime ideals are discussed. It is shown that generalized lower approximation as well as generalized upper approximation of (∈ , ∈∨q)-fuzzy prime (semiprime) ideals ...
Muhammad Rameez   +2 more
doaj  

Semirings which have linearly ordered prime ideals

open access: yes, 2019
As a generalization of valuation semirings, the main purpose of this paper is to investigate those semirings that their prime ideals are totally ordered by inclusion.
Behzadipour, H., Nasehpour, P.
core  

Evaluating a Pragmatic Strength Alternative for Frailty Measurement and Assessing Its Predictive Capacity Against Established Frailty Instruments in Rheumatoid Arthritis

open access: yesArthritis Care &Research, EarlyView.
Objective Frailty occurs prematurely in rheumatoid arthritis (RA) and is associated with poor health outcomes. We compared the performance of four frailty instruments, including a pragmatic alternative measure using chair sit‐to‐stand (STS), and evaluated their abilities to predict poor health outcomes.
Kylie E. Riggles   +14 more
wiley   +1 more source

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh   +5 more
wiley   +1 more source

On Hadamard algebras

open access: yesLe Matematiche, 2000
Topological algebras of sequences of complex numbers are introduced, endowed with a Hadamard product type. The complex homomorphisms on these algebras are characterized, and units, prime cyclic ideals, prime closed ideals, and prime minimal ideals ...
Carlos C. Peña
doaj  

Minimal primes over permanental ideals [PDF]

open access: yesTransactions of the American Mathematical Society, 2008
In this paper we discuss minimal primes over permanental ideals of generic matrices. We give a complete list of the minimal primes over ideals of 3 x 3 permanents of a generic matrix, and show that there are monomials in the ideal of maximal permanents of a d x 2d-1 matrix if the characteristic of the ground field is sufficiently large. We also discuss
openaire   +3 more sources

Trajectories of Physical Function in Canadian Children with Juvenile Idiopathic Arthritis

open access: yesArthritis Care &Research, Accepted Article.
Objectives We describe trajectories of physical function in children newly diagnosed with juvenile idiopathic arthritis (JIA) and identify trajectories with persisting functional impairments and associated baseline characteristics. Methods We included patients enrolled in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry ...
Clare Cunningham   +14 more
wiley   +1 more source

On Fuzzy Ideals of BL-Algebras

open access: yesThe Scientific World Journal, 2014
In this paper we investigate further properties of fuzzy ideals of a BL-algebra. The notions of fuzzy prime ideals, fuzzy irreducible ideals, and fuzzy Gödel ideals of a BL-algebra are introduced and their several properties are investigated.
Biao Long Meng, Xiao Long Xin
doaj   +1 more source

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