Results 61 to 70 of about 1,802,459 (260)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Multiscale Sieve for Smart Prime Generation and Application in Info-Security, IoT and Blockchain
Applied SciencesThe huge computational cost required to test whether a number is prime and the inefficiency of the known sieving algorithms for extremely large inputs have posed significant challenges in computational number theory.
Gerardo Iovane +2 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Open MathematicsIn the context of a simple undirected graph GG, a kk-prime labeling refers to assigning distinct integers from the set {k,k+1,…,∣V(G)∣+k−1}\left\{k,k+1,\ldots ,| V\left(G)| +k-1\right\} to its vertices, such that adjacent vertices in GG are labeled with ...
Abughneim Omar A., Abughazaleh Baha’
doaj +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Subsets of prime numbers received by means of generalized arithmetic progression
Дифференциальная геометрия многообразий фигур, 2018 A short historical information about formulas and polynomials generating subsets of prime numbers is given. Examples of subsets of prime numbers by using generalized arithmetic progression are obtained.
V. Malakhovsky
doaj
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Thinking over the Goldbach conjecture solution from a probabilistic point of view
Ratio MathematicaThis paper aims to provide a set of considerations that allow us to see a possible solution to the problematic issue of Goldbach's "strong" conjecture, which amounts to asserting that any even natural number greater than 2 can be written as the sum of ...
Rosario D'Amico
doaj +1 more source
Prime number logarithmic geometry on the plane
, 2002 We found a regularity of the behavior of primes that allows to represent both prime and natural numbers as infinite matrices with a common formation rule of their rows.
Alexandrov, Lubomir
core +2 more sources
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source