Results 211 to 220 of about 147,553 (263)

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Strong immunogenicity and protection against SARS-CoV-2 in hamsters induced by heterologous boost vaccination with an MVA-based COVID-19 vaccine candidate. [PDF]

J Gen Virol
Ohrnberger S, Meyer Zu Natrup C, Clever S, Schünemann LM, Armando F, Ciurkiewicz M, Baumgärtner W, Kalodimou G, Sutter G, Tscherne A, Volz A.   +10 more
europepmc   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Social isolation/vulnerability and support for loneliness in a rural Japanese cohort: a questionnaire-based observational study. [PDF]

J Rural Med
Hisata Y, Ueda Y, Urayama M, Katsuki NE, Tago M, Higashino K, Naya Y.   +6 more
europepmc   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

A collaborative multi-party encryption for mitigating man-in-the-middle attacks in smart grid and energy IoT systems. [PDF]

Sci Rep
Alfawair M.
europepmc   +1 more source

Analogs of the Prime Number Problem in a Shot Noise Suppression of the Soft-Reset Process. [PDF]

Nanomaterials (Basel)
Hirose Y.
europepmc   +1 more source

Effect of dimethyl sulfoxide on the resin-dentin bond strength of universal adhesives after thermocycling. [PDF]

Front Dent Med
Kotan MH, Bayındır YZ.
europepmc   +1 more source

Playing With Matches: Preparatory Cognitive Processing Shapes Affective Evaluation. [PDF]

J Cogn
Weis PP, Kunde W, Wirth R.
europepmc   +1 more source

Combating respiratory diseases with mucosal vaccines. [PDF]

J Virol
Tang PCH, Ling Z, Lee M, King NJC, Mahalingam S.   +4 more
europepmc   +1 more source