Results 51 to 60 of about 441,153 (259)

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

On generalized homoderivations of prime rings

open access: yesМатематичні Студії, 2023
Let $\mathscr{A}$ be a ring with its center $\mathscr{Z}(\mathscr{A}).$ An additive mapping $\xi\colon \mathscr{A}\to \mathscr{A}$ is called a homoderivation on $\mathscr{A}$ if $\forall\ a,b\in \mathscr{A}\colon\quad \xi(ab)=\xi(a)\xi(b)+\xi(a)b+a\xi(
N. Rehman   +2 more
doaj   +1 more source

On Polynomial Rings Over Nil Rings in Several Variables and the Central Closure of Prime Nil Rings

open access: yes, 2016
We prove that the ring of polynomials in several commuting indeterminates over a nil ring cannot be homomorphically mapped onto a ring with identity, i.e. it is Brown-McCoy radical. It answers a question posed by Puczylowski and Smoktunowicz.
Chebotar, Mikhail   +3 more
core   +1 more source

Rewriting the dendritic cell code in cancer—from subset identity to immunotherapeutic design

open access: yesFEBS Letters, EarlyView.
Dendritic cells (DCs) play central roles in cancer immunity but are often subverted by the tumor microenvironment. This review explores the diversity of DC subsets, their functional plasticity, and emerging therapeutic strategies to reprogram DCs for enhanced antitumor responses, including vaccines, in vivo targeting, and DC‐based immunotherapies ...
Estevão Carlos Silva Barcelos   +3 more
wiley   +1 more source

$\mathscr{T}$-Commuting Generalized Derivations on Ideals and Semi-Prime Ideal-II

open access: yesМатематичні Студії, 2022
The study's primary purpose is to investigate the $\mathscr{A}/\mathscr{T}$ structure of a quotient ring, where $\mathscr{A}$ is an arbitrary ring and $\mathscr{T}$ is a semi-prime ideal of $\mathscr{A}$.
N. U. Rehman, H. M. Alnoghashi
doaj   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

(θ1,θ2) - Derivation Pair on Rings

open access: yesIbn Al-Haitham Journal for Pure and Applied Sciences, 2022
Ring theory is one of the influential branches of abstract algebra. In this field, many algebraic problems have been considered by mathematical researchers who are working in this field.
Mohammed Khalid Shahoodh
doaj   +1 more source

Mycobacterium tuberculosis sulfurtransferase SseA is activated by its neighboring gene product Rv3284

open access: yesFEBS Letters, EarlyView.
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli   +10 more
wiley   +1 more source

ON DIFFERENTIAL IDEALS OF DIFFERENTIAL RINGS [PDF]

open access: yesمجلة جامعة الانبار للعلوم الصرفة, 2012
In this paper we introduce two operators denoted by and of a differential ring constructed from a subset of a differential ring. We shall also discuss the relationship between these operators and the differential ideals in differential rings, and Keigher
Yaseen A.W. Alhiti
doaj   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

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