Results 71 to 80 of about 44,957 (356)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
A THEOREM ON DERIVATIONS ON PRIME RINGS [PDF]
Journal of the Australian Mathematical Society, 2011 AbstractLet R be a prime ring, let I be a nonzero ideal of R and let n be a fixed positive integer. We prove that if the characteristic of R is either 0 or a prime p that is greater than 2n, then an additive map d that satisfies d(xn+1)=∑ nj=0xn−jd(x)xj for all x∈I must be a derivation.
openaire +2 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Characterization of rings with planar, toroidal or projective planar prime ideal sum graphs
AKCE International Journal of Graphs and CombinatoricsLet R be a commutative ring with unity. The prime ideal sum graph [Formula: see text] of the ring R is the simple undirected graph whose vertex set is the set of all nonzero proper ideals of R and two distinct vertices I and J are adjacent if and only if
Praveen Mathil +3 more
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
ON DIFFERENTIAL IDEALS OF DIFFERENTIAL RINGS [PDF]
مجلة جامعة الانبار للعلوم الصرفة, 2012 In this paper we introduce two operators denoted by and of a differential ring constructed from a subset of a differential ring. We shall also discuss the relationship between these operators and the differential ideals in differential rings, and Keigher
Yaseen A.W. Alhiti
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The prime ideals intersection graph of a ring [PDF]
, 2017 summary:Let $R$ be a commutative ring with unity and $U(R)$ be the set of unit elements of $R$. In this paper, we introduce and investigate some properties of a new kind of graph on the ring $R$, namely, the prime ideals intersection graph of $R ...
Nikmehr, M. J., Soleymanzadeh, B.
core +1 more source
On finiteness of rings with finite maximal subrings
International Journal of Mathematics and Mathematical Sciences, 1993 It is conjectured that every ring with a finite maximal subring is finite. We prove this conjecture for PI-rings.
H. E. Bell, A. A. Klein
doaj +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source