Results 61 to 70 of about 44,957 (356)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Rigidity and exotic models for the K-local stable homotopy category [PDF]

open access: yes, 2007
Can the model structure of a stable model category be recovered from the triangulated structure of its homotopy category? This paper introduces a new positive example for this, namely the K-local stable homotopy at the prime 2.
Roitzheim, C., Roitzheim, Constanze
core   +1 more source

$\mathscr{T}$-Commuting Generalized Derivations on Ideals and Semi-Prime Ideal-II

open access: yesМатематичні Студії, 2022
The study's primary purpose is to investigate the $\mathscr{A}/\mathscr{T}$ structure of a quotient ring, where $\mathscr{A}$ is an arbitrary ring and $\mathscr{T}$ is a semi-prime ideal of $\mathscr{A}$.
N. U. Rehman, H. M. Alnoghashi
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Primitive ideals and automorphisms of quantum matrices. [PDF]

open access: yes, 2007
Let K be a field and q be a nonzero element of K that is not a root of unity. We give a criterion for (0) to be a primitive ideal of the algebra O-q(M-m,M-n) of quantum matrices.
Lenagan, T.H.   +3 more
core   +1 more source

(θ1,θ2) - Derivation Pair on Rings

open access: yesIbn Al-Haitham Journal for Pure and Applied Sciences, 2022
Ring theory is one of the influential branches of abstract algebra. In this field, many algebraic problems have been considered by mathematical researchers who are working in this field.
Mohammed Khalid Shahoodh
doaj   +1 more source

Prime (-1, 1) Rings with Idempotent [PDF]

open access: yesProceedings of the American Mathematical Society, 1967
Algebras of type \((\gamma,\delta)\)) were first defined by \textit{A. A. Albert} [Port. Math. 8, 23--36 (1949; Zbl 0033.15401)]. In a 1963 paper [Proc. Am. Math. Soc. 14, 110--117 (1963; Zbl 0108.26101)] \textit{C. Maneri} showed that a simple \((-1,1)\) ring with a nontrivial idempotent and characteristic prime to 6 must be associative.
openaire   +1 more source

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