Results 81 to 90 of about 204,704 (282)

Prime Ideals and Strongly Prime Ideals of Skew Laurent Polynomial Rings

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2008
We first study connections between α-compatible ideals of R and related ideals of the skew Laurent polynomials ring R[x,x−1;α], where α is an automorphism of R.
E. Hashemi
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Prime elements and prime sequences in polynomial rings [PDF]

open access: yesProceedings of the American Mathematical Society, 1978
The central question of this note concerns the existence of prime elements in polynomial rings. In it are established for polynomial rings over arbitrary noetherian rings—insofar as is generally possible—certain results concerning bases for maximal ideals, well known for polynomial rings over fields and principal ideal domains.
openaire   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Characterization of rings with planar, toroidal or projective planar prime ideal sum graphs

open access: yesAKCE International Journal of Graphs and Combinatorics
Let R be a commutative ring with unity. The prime ideal sum graph [Formula: see text] of the ring R is the simple undirected graph whose vertex set is the set of all nonzero proper ideals of R and two distinct vertices I and J are adjacent if and only if
Praveen Mathil   +3 more
doaj   +1 more source

Prime Structures in a Morita Context

open access: yes, 2018
In this paper, we study on the primeness and semiprimeness of a Morita context related to the rings and modules. Necessary and sufficient conditions are investigated for an ideal of a Morita context to be a prime ideal and a semiprime ideal.
Calci, Mete Burak   +3 more
core  

Prime Ideals in Enveloping Rings [PDF]

open access: yesTransactions of the American Mathematical Society, 1987
Let L L be a Lie algebra over the field K K of characteristic 0 0 and let U ( L ) U(L) denote its universal enveloping algebra. If R R is a K K -algebra and L L acts on R R as ...
openaire   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

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