Results 111 to 120 of about 78,445 (293)
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
On the prime spectrum of modules [PDF]
Miskolc Mathematical Notes, 2015 Ansari-Toroghy, H. +1 more
openaire +2 more sources
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta +7 more
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Selçuk İletişim, 2013 Using content analysis of four national newspapers in Turkey and applying framing analysis, this study examines how the selected newspapers framed the image of Turkish Prime Minister Erdoğan and national image of Turkey after the Davos incident in World ...
Elif Engin, Güler Şener
doaj
Prime ideals in two-dimensional polynomial rings
, 1989 We show that for every nonzero prime ideal P P in a Noetherian domain R R there are either just one or infinitely many prime ideals of the absolute integral closure of R R lying over P P
William Heinzer, Sylvia Wiegand
core +1 more source
FEBS Open Bio, EarlyView.TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
Combined Prime Codes for Optical Spread Spectrum Communication
, 2014 在光纖展頻通訊中, 若使用質數值為P之修正質數碼做為展頻碼,它的長度為P/sup 2/chips, 但其解碼容量卻只有P/sup 2/個。若需要較大之解碼容量時, 必須使用較大之P值而使得展頻碼可能太長而不切實際。本論文改用由多個質數P/sub 1/、P/sub 2/...P/sub k/之修正質數碼所合併的新碼做為展頻碼, 結果只需(P/sup 2//sub 1/+P/sup 2//sub 2/+Λ+P/sup 2//sub k/) chips之長度即能擁有(P/sup 2//sub 1/×P/sup
李揚漢; 楊中碩; 趙亮琳 +1 more
core
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source