Results 71 to 80 of about 78,445 (293)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

A note on Sturm-Liouville problems whose spectrum is the set of prime numbers

open access: yesElectronic Journal of Differential Equations, 2011
We show that there is no classical regular Sturm-Liouville problem on a finite interval whose spectrum consists of infinitely many distinct primes numbers. In particular, this answers in the negative a question raised by Zettl in his book [9].
Angelo B. Mingarelli
doaj  

On the second spectrum of lattice modules

open access: yesDiscussiones Mathematicae - General Algebra and Applications, 2017
The second spectrum Specs(M) is the collection of all second elements of M. In this paper, we study the topology on Specs(M), which is a generalization of the Zariski topology on the prime spectrum of lattice modules. Besides some properties, Specs(M) is
Phadatare Narayan   +2 more
doaj   +1 more source

The equality of the Patch topology and the Ultrafilter topology: A shortcut

open access: yesApplied General Topology, 2011
In this work R denotes a commutative ring with non-zero identity andwe prove that the patch topology and the ultrafilter topology definedon the prime spectrum of R are equal, in a different way as the givenby Marco Fontana and K.
Luz M. Ruza, Jorge Vielma
doaj   +1 more source

Prime spectra in modular varieties

open access: yes, 1993
By using the concept of modular commutator, prime congruences are defined for algebras in modular varieties. Then the prime spectrum of an algebra is defined and various spectral properties are discussed.
AGLIANO', PAOLO
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Accurate single- and double-differential resummation of colour-singlet processes with MATRIX+RADISH: W + W − production at the LHC

open access: yesJournal of High Energy Physics, 2020
We present the combination of fully differential cross sections for colour-singlet production processes at next-to-next-to-leading order (NNLO) QCD obtained with Matrix and all-order resummation through RadISH.
Stefan Kallweit   +3 more
doaj   +1 more source

Representations of commutative rings via the prime spectrum [PDF]

open access: yes, 2019
Given a commutative noetherian ring R we discuss its representations, i.e. its R-modules. The prime spectrum of R plays a fundamental role, controlling much of the structure of the category of R-modules. We illustrate this in two instances, surveying a
Vitoria, Jorge
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

The Prime Spectrum and Representation Theory of Generalized Weyl Algebras, with Applications to Quantized Algebras [PDF]

open access: yes, 2018
This work develops the theory of generalized Weyl algebras (GWAs) in order to study generic quantized algebras. The ideas behind the classification of simple modules over GWAs are used to describe the noncommutative prime spectrum for certain GWAs.
Ebrahim, Ebrahim
core  

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