Results 61 to 70 of about 1,409,327 (243)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
One-step RT-PCR to detect tick-borne encephalitis virus infection
One Health & Risk Management, 2023 Introduction. Tick-borne encephalitis (TBE) is a significant zoonotic disease found in endemic areas. It is the most common viral cause of central nervous system diseases in humans and is caused by the tick-borne encephalitis virus (TBEV).
Olga SOFRONIE
doaj
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Surface modification for bonding between amalgam and orthodontic brackets
Journal of Orthodontic Science, 2017 Objective: Testing of methods to enhance the shear bond strength (SBS) between orthodontic metal brackets and amalgam by sandblasting and different primers.
Wittawat Wongsamut +2 more
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
REAL TIME POLYMERASE CHAIN REACTION IN TULAREMIA LABORATORY DIAGNOSTICS
Журнал микробиологии, эпидемиологии и иммунобиологии, 2015 Aim. Enhancement of tularemia laboratory diagnostics by F. tularensis DNA determination in blood sera of patients using real time polymerase chain reaction (RT-PCR). Materials and methods.
M. I Kormilitsyna +3 more
doaj
Western Pacific Surveillance and Response, 2019 Introduction: There are two methods of reverse transcription polymerase chain reaction (RT–PCR) that have been the common methods to detect influenza infections: conventional and real-time RT–PCR.
Hoang Vu Mai Phuong +9 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
In vitro evaluation of shear bond strength of orthodontic brackets bonded with different adhesives
Contemporary Clinical Dentistry, 2018 Background: There is necessary of dry operating field for bonding of orthodontic brackets. The presence of moisture can alter the bond strength. Hence, the aim of the present study was to evaluate the shear bond strength of orthodontic brackets with ...
Junaid Ahmed Shaik +5 more
doaj +1 more source