Results 81 to 90 of about 1,409,327 (243)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Аграрная наука Евро-Северо-ВостокаGrafting of vegetable crops is widely used in industrial vegetable growing in Asia and Western Europe. However, the influence of the genetic relationship of the scion and rootstock, the activity of peroxidase and the content of ascorbic acid in the ...
S. А. Musikhin +2 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Identification of toxic and non-toxic Microcystis by three primers
, 2004 To discriminate from toxic and non-toxic Microcystis, 3 pairs of primers epF/mb1R, mcF/teR and mcF/umR were designed, based on sequences of microcystin synthetase gene cluster.
Song Li-rong (lrsong@ihb.ac.cn) +4 more
core
Fungal-specific PCR primers developed for analysis of the ITS region of environmental DNA extracts
BMC Microbiology, 2005 Background The Internal Transcribed Spacer (ITS) regions of fungal ribosomal DNA (rDNA) are highly variable sequences of great importance in distinguishing fungal species by PCR analysis.
Rygiewicz Paul T, Martin Kendall J
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Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Detection of Tilletia controversa and Tilletia caries in wheat by PCR method
Plant, Soil and Environment, 2004 Tilletia controversa and Tilletia caries were specifically detected in wheat plants by PCR using primers TILf (5´-CAC AAG ACT ACG GAG GGG TG-3´) and TILr (5´-CTC CAA GCA ACC TTC TCT TTC-3´).
M. Kochanová +3 more
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The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Applicability of cetacean microsatellite primers in the Yangtze finless porpoise
, 2004 Application of microsatellites in the Yangtze finless porpoise ( Neophocaena phocaenoides asiaeorientalis) has not been reported. In this study amplification of microsatellites were performed in DNA samples of the Yangtze finless porpoise population by ...
Wang Ding (wangd@ihb.ac.cn) +3 more
core
Journal of Oral Microbiology, 2014 Background and objective: In addition to the well-known phyla Firmicutes, Proteobacteria, Bacteroidetes, Actinobacteria, Spirochaetes, Fusobacteria, Tenericutes, and Chylamydiae, the oral microbiomes of mammals contain species from the lesser-known phyla
Anuj Camanocha, Floyd E. Dewhirst
doaj +1 more source