Results 111 to 120 of about 526,644 (315)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Phonaesthemes: non-arbitrariness in the mental lexicon?

open access: yesMiranda: Revue Pluridisciplinaire du Monde Anglophone, 2012
For the most part, the sounds of words in a language are arbitrary, given their meanings. But in fact, there are two ways in which words can be non-arbitrary.
Benjamin Bergen
doaj   +1 more source

Human frontal eye fields and spatial priming of pop-out [PDF]

open access: yes, 2007
"Priming of pop-out" is a form of implicit memory that facilitates detection of a recently inspected search target. Repeated presentation of a target's features or its spatial position improves detection speed (feature/spatial priming).
Cowey, A   +3 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Age effects on explicit and implicit memory

open access: yesFrontiers in Psychology, 2013
It is well documented that explicit memory (e.g., recognition) declines with age. In contrast, many argue that implicit memory (e.g., priming) is preserved in healthy aging.
Emma eWard, Chris eBerry, David eShanks
doaj   +1 more source

Worker Retention, Response Quality, and Diversity in Microtask Crowdsourcing: An Experimental Investigation of the Potential for Priming Effects to Promote Project Goals [PDF]

open access: yes, 2018
Online microtask crowdsourcing platforms act as efficient resources for delegating small units of work, gathering data, generating ideas, and more.
Colombini, Brian J
core   +1 more source

The role of the posterior fusiform gyrus in reading [PDF]

open access: yes, 2006
Studies of skilled reading [Price, C. J., & Mechelli, A. Reading and reading disturbance. Current Opinion in Neurobiology, 15, 231–238, 2005], its acquisition in children [Shaywitz, B. A., Shaywitz, S. E., Pugh, K. R., Mencl, W. E., Fulbright, R.
Devlin, J.T.   +3 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Induction of Systemic Resistance against Insect Herbivores in Plants by Beneficial Soil Microbes

open access: yesFrontiers in Plant Science, 2017
Soil microorganisms with growth-promoting activities in plants, including rhizobacteria and rhizofungi, can improve plant health in a variety of different ways. These beneficial microbes may confer broad-spectrum resistance to insect herbivores. Here, we
Md. Harun-Or Rashid, Young R. Chung
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

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