Results 71 to 80 of about 8,580,336 (264)

Setting Incentives for Collaboration Among Agricultural Scientists: Application of Principal-Agent Theory to Team Work [PDF]

The USDA is attempting to shift more research funds into competitive grants involving collaboration across disciplines on large projects. This type of research structure raises a host of information and incentive issues.
Wallace E. Huffman
core  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

The Effect of Medical Choice on Health Costs of Middle-Aged and Elderly Patients with Chronic Disease: Based on Principal-Agent Theory. [PDF]

Int J Environ Res Public Health, 2022
Li D, Su M, Guo X, Zhang W, Zhang T.
europepmc   +1 more source

A Principal-Agent Analysis of the Family: Implications for the Welfare State [PDF]

The principal-agent literature has focussed on situations where both principal and agent are assumed to be capable of defining and defending their own interests.
Munro, Lauchlan
core  

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

How Supervision Failures Lead to Quality Risk of Land Trusteeship Services: A Principal–Agent Theory Perspective

Land
The service quality of land trusteeship is often subpar due to farmers’ ineffective supervision of service providers’ opportunistic behaviors. However, the existing literature has not given much attention to this agency issue from the principal–agent ...
Lianghong Yu, Shan Zheng, Kun Gao
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Can the behavioral agency model refine a standard agency theory?

Journal of Enterprise and Development
Purpose — The existence of agency problems is widely recognized in various academic fields. Nevertheless, as argued by many scholars, agency theory has obvious shortcomings both theoretically and empirically.
Muhammad Masyhuri
doaj   +1 more source

Imprecise Beliefs in a Principal Agent Model [PDF]

This paper presents a principal-agent model where the agent has multiple, or imprecise, beliefs. We model this situation formally by assuming the agent's preferences are incomplete.
Rigotti, L.
core  

Principal-Agent Theory and the World Trade Organization: Complex Agency and ‘Missing Delegation’ [PDF]

, 2011
This paper analyses the World Trade Organization within a principal-agent framework. The concept of complex agency is introduced to focus on the variety of actors that comprise an international organization.
Elsig, Manfred
core   +1 more source