Results 41 to 50 of about 658,976 (287)

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Study on the project supervision system based on the principal-agent theory

Journal of Industrial Engineering and Management, 2015
Purpose: In order to solve problems in the current project management system, the paper presents the asymmetric information games existing in construction projects through information economics viewpoints.Design/methodology/approach: The owner has ...
Runtong Zhang, Yang Zhou, Hongnan Zhuang, Xiaomin Zhu   +3 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Venture Investment Incentive Mechanisms and Simulation with Venture Entrepreneurs Having Multistage Efforts Based on Fairness Preference Theory

Discrete Dynamics in Nature and Society, 2016
When venture capital has been invested into venture companies, venture capitalists and venture entrepreneurs form a principal-agent relationship. Take into account the fact that the venture entrepreneur’s effort is a long process, because the effort is ...
Kaihong Wang, Chuan Ding, Jiacheng Chen, Aimin Li   +3 more
doaj   +1 more source

Corporate governance criteria as applied in private equity investments

South African Journal of Business Management, 2005
Ineffective governance has often formed a backdrop to corporate failure with the resultant negative impact on stakeholders. In the field of private equity, investors have consistently received financial returns that outperform those of listed equities ...
R. Millson, M. Ward
doaj   +1 more source

Citizen Relationship Management and Principal/Agent Theory

International Journal of Managing Value and Supply Chains, 2014
Principal/Agent Theory economic that makes clear accountability relationship management (Agent) to shareholders (Principal), Have the effect of creating new public management . This theory highlights important issues regarding the accountability of state structures that distinguishes private structures.
Ameneh Malmir, Alireza Shirvani, Ali Rashidpour, Iraj Soltani   +3 more
openaire   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Investigating the Relationship Between Entity Financialization, Managers’ Incentives, and Enterprise’s Innovation: Fresh Evidence From China

Frontiers in Psychology, 2022
The current study examines the relationship between financialization, managers’ incentives, and the enterprise’s innovation. Based on the principal-agent and incentive theories, this study proposes a research model with two management incentives as ...
Chaohui Xu, Haikuan Zhang, Haikuan Zhang, Haikuan Zhang, Mansi Wang, Mansi Wang, Amir Iqbal   +6 more
doaj   +1 more source

The appeals process in principal–agent relationships [PDF]

Journal of Economic Behavior & Organization, 2009
Abstract The appeals process is employed in many organizations including administrative agencies, regulatory authorities, sports organizations, and private companies. This paper examines the dual role of the appeals process in enhancing fairness and inducing performance in principal–agent relationships in the presence of imperfect performance ...
openaire   +1 more source

What Drives Renewal of Sponsorship Principal/Agent Relationships? [PDF]

Journal of Advertising Research, 2003
The relationship between advertising agencies and their clients has been the subject of some research, including studies conceptualizing it from an agency theory perspective. The increasingly important relationship between sports (or art) properties and their sponsors, on the other hand, while recognized as crucial for the long-term success of the ...
Farrelly, F., Quester, P. G.
openaire   +3 more sources