Results 91 to 100 of about 3,803,712 (257)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Image encoding by independent principal components [PDF]

open access: yes, 2010
The encoding of images by semantic entities is still an unresolved task. This paper proposes the encoding of images by only a few important components or image primitives. Classically, this can be done by the Principal Component Analysis (PCA). Recently,
Brause, Rüdiger W., Arlt, Björn
core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

A Principal-Agent Analysis of the Family: Implications for the Welfare State [PDF]

open access: yes
The principal-agent literature has focussed on situations where both principal and agent are assumed to be capable of defining and defending their own interests.
Munro, Lauchlan
core  

Principal Lecturer to Principal Fellow: on cloud nine with a few clouds in between [PDF]

open access: yes, 2016
Dr Heather Prince is Associate Professor of Outdoor and Environmental Education/Principal Lecturer at University of Cumbria. In this Higher Education Academy blog post she talks about her journey to becoming a Principal Fellow of the HEA (PFHEA), and the
Prince, Heather
core  

Una vendetta ossia La sposa di Murcia : [Texto impreso] libretto in tre atti [PDF]

open access: yes
Escrita expresamente para ser representada en el Teatro Principal de ...
Agostini, Angelo   +1 more
core   +3 more sources

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

The Quality-Quantity Trade-off in the Principal-Agent Framework [PDF]

open access: yes
This paper uses the principal-agent theory to analytically investigate the optimal incentive-based compensation contract that a processor should offer to a grower performing efforts in quantity and quality.
Olmos, Marta Fernandez   +1 more
core  

Cultural Leadership Roles of School Principals

open access: yesKuramsal Eğitimbilim Dergisi, 2012
The purpose of this study is to examine cultural leadership roles of school principals in high schools as effective schools. In this study, the effects of of variables, such as gender, professional status, and experience were examined.
Sinan YÖRÜK, Bahar ŞAHİN
doaj  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

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