Results 61 to 70 of about 173,695 (219)

The perspectives of beginner principals on their new roles in school leadership and management: A South African case study

South African Journal of Education, 2020
In the study reported on here we aimed to explore how beginner principals perceived their roles as new appointees. School principals are expected to demonstrate proficiency when performing leadership and management roles in schools.
Malesela Gilbert Sepuru , Mokgadi Agnes Mohlakwana   +1 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

PRINCIPAL LEADERSHIP STYLE AND ITS EFFECT ON TEACHERS PERFORMANCE

Jurnal Aplikasi Manajemen, 2019
This study aims to analyze the effect of the application of leadership style on the teacher’s performance and the dominant leadership style on the teacher’s performance.
Elpisah Elpisah, Hartini Hartini
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

KEPEMIMPINAN KEPALA SEKOLAH DALAM UPAYA PENINGKATAN KINERJA GURU (STUDI MULTI KASUS DI PAUD ISLAM SABILILLAH DAN SDN TANJUNGSARI 1 KABUPATEN SIDOARJO)

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan, 2016
The purpose of this study was to: (1) describe the leadership style of the principal in improving teacher performance; (2) describe the role of the school principal; (3) describe the factor endowments and a barrier in improving the performance of ...
Wahyu Ramadoni, Kusmintardjo Kusmintardjo, Imron Arifin   +2 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

IMPLEMENTASI KEPEMIMPINAN KEPALA MAN DALAM MEMBANGUN BUDAYA MUTU DI KOTA MATARAM

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan, 2016
The Focus is to describes: (1) services quality, (2) teachers and staffs quality, (3) facilities quality. This study used a qualitative approach with multi-site study design.
Nurhasanah Nurhasanah, Ahmad Sonhadji, K.H. Ali Imron   +2 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source