Results 101 to 110 of about 2,362,828 (289)

A characterization of Jacobians by the existence of Picard bundles

open access: yesLe Matematiche, 2008
Based on the Matsusaka-Ran criterion we give a criterion to characterize when a principal polarized abelian variety is a Jacobian by the existence of Picard bundles.
Ana C. López Martín   +2 more
doaj  

Threshold corrections in heterotic flux compactifications

open access: yesJournal of High Energy Physics, 2017
We compute the one-loop threshold corrections to the gauge and gravitational couplings for a large class of N = 2 $$ \mathcal{N}=2 $$ non-Kähler heterotic compactifications with three-form flux, consisting in principal two-torus bundles over K3 surfaces.
Carlo Angelantonj   +2 more
doaj   +1 more source

a review of Diffeological principal bundles and principal infinity bundles. by Minichiello, Emilio [PDF]

open access: yesa review of Diffeological principal bundles and principal infinity bundles. by Minichiello, Emilio
Hirokazu Nishimura
openaire   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Strong generalized holomorphic principal bundles [PDF]

open access: yes
We introduce the notion of a strong generalized holomorphic (SGH) fiber bundle and develop connection and curvature theory for an SGH principal $G$-bundle over a regular generalized complex (GC) manifold, where $G$ is a complex Lie group. We develop a de
Poddar, Mainak, Pal, Debjit
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

The Temporal and Spatial Evolution Characteristics and Driving Factors of Ecosystem Service Bundles in Anhui Province, China

open access: yesLand
Identifying ecosystem service bundles and their long-term evolutionary characteristics is essential for the overall enhancement of regional ecosystem services, as well as the division and management of functional areas, providing a basis for decision ...
Zhongjian Mei   +6 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy