Results 71 to 80 of about 811,918 (310)
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Principal component analysis for three-dimensional structured illumination microscopy (PCA-3DSIM)
Light: Science & ApplicationsThree-dimensional structured illumination microscopy (3DSIM) is an essential super-resolution imaging technique for visualizing volumetric subcellular structures at the nanoscale, capable of doubling both lateral and axial resolution beyond the ...
Jiaming Qian +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli +9 more
wiley +1 more source
Uncertainty-Aware Principal Component Analysis
, 2019 We present a technique to perform dimensionality reduction on data that is subject to uncertainty. Our method is a generalization of traditional principal component analysis (PCA) to multivariate probability distributions.
Deussen, Oliver +4 more
core +1 more source
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Nucleic Acids Res., 2015 The Principal Component Analysis (PCA) is a widely used method of reducing the dimensionality of high-dimensional data, often followed by visualizing two of the components on the scatterplot. Although widely used, the method is lacking an easy-to-use web
Tauno Metsalu, J. Vilo
semanticscholar +1 more source
Principal Components Analysis for the Interpretation of Humidification Phenomena—Preliminary Results
Proceedings, 2019 Moisture is one of the major causes of building decay, compromising the indoor air quality and the durability of building components. Infrared thermography is a non-destructive technique that can be used to prevent damage caused by the presence of water.
Eva Barreira +3 more
doaj +1 more source
Jurnal Teknologi Informasi dan Ilmu Komputer, 2020 Pengamatan citra Pap Smear merupakan langkah yang sangat penting dalam mendiagnosis awal terhadap gangguan servik. Pengamatan tersebut membutuhkan sumber daya yang besar. Dalam hal ini machine learning dapat mengatasi masalah tersebut.
Krisan Aprian Widagdo +2 more
doaj +1 more source
Journal of Spectroscopy, 2021 To facilitate the enhanced reliability of Raman-based tumor detection and analytical methodologies, an ex vivo Raman spectral investigation was conducted to identify distinct compositional information of healthy (H), ductal carcinoma in situ (DCIS), and ...
Heping Li +7 more
doaj +1 more source