Results 171 to 180 of about 5,566,031 (259)

Can Unsupervised Machine Learning Support Malnutrition Risk Screening in Older Adults? A Preliminary Study Using Multidimensional Phenotyping and Hierarchical Clustering on Principal Components. [PDF]

Nutrients
Kujawowicz K, Mirończuk-Chodakowska I, Cyuńczyk M, Witkowska AM.   +3 more
europepmc   +1 more source

Author Correction: mbDenoise: microbiome data denoising using zero-inflated probabilistic principal components analysis. [PDF]

Genome Biol, 2023
Zeng Y, Li J, Wei C, Zhao H, Wang T.
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Body composition-derived principal components partially explain sex and age effects on bone mineral density in type 2 diabetes mellitus. [PDF]

Front Endocrinol (Lausanne)
Cheng D, Chen Y, Cai Y, Wang J, Yang S, Mao J, Wang Y.   +6 more
europepmc   +1 more source

ERStruct: a fast Python package for inferring the number of top principal components from whole genome sequencing data. [PDF]

BMC Bioinformatics, 2023
Yang J, Xu Y, Yao M, Wang G, Liu Z.
europepmc   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

randPedPCA: rapid approximation of principal components from large pedigrees. [PDF]

Genet Sel Evol
Lee H, Craddock RF, Gorjanc G, Becher H.
europepmc   +1 more source

Principal components from untargeted cerebrospinal fluid metabolomics associated with Alzheimer's disease biomarkers. [PDF]

Neurobiol Aging, 2022
Dong R, Denier-Fields DN, Lu Q, Suridjan I, Kollmorgen G, Wild N, Betthauser TJ, Carlsson CM, Asthana S, Johnson SC, Zetterberg H, Blennow K, Engelman CD.   +12 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Association of Nontraditional Lipid Parameters With Long-Term Prognosis of Acute Ischemic Stroke: A Principal Components Analysis. [PDF]

J Am Heart Assoc
Lin H, Xie W, Huang S, Lou J, Zhang R, Yu B, Zhou G, Pan Y, Wu T, Huang X, Chen F, Zhang C, Zhu Y, Weng Y, Yang D, Chen G.   +15 more
europepmc   +1 more source