Results 61 to 70 of about 2,352,425 (243)
Principal components' features of mid-latitude geomagnetic daily variation [PDF]
Annales Geophysicae, 2010 The ionospheric and magnetospheric current systems are responsible of the daily magnetic field changes. Recently, the Natural Orthogonal Components (NOC) technique has been applied to model the physical system responsible of the daily variation of the
P. De Michelis +3 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Common Functional Principal Components [PDF]
Functional principal component analysis (FPCA) based on the Karhunen-Lo`eve decomposition has been successfully applied in many applications, mainly for one sample problems.
Alois Kneip +2 more
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Mining gene expression data by interpreting principal components
BMC Bioinformatics, 2006 Background There are many methods for analyzing microarray data that group together genes having similar patterns of expression over all conditions tested. However, in many instances the biologically important goal is to identify relatively small sets of
Mortazavi Ali +5 more
doaj +1 more source
The principal independent components of images [PDF]
This paper proposes a new approach for the encoding of images by only a few important components. Classically, this is done by the Principal Component Analysis (PCA).
Arlt, Björn, Brause, Rüdiger W.
core
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Linear Dimensionality Reduction: What Is Better?
DataThis research paper focuses on dimensionality reduction, which is a major subproblem in any data processing operation. Dimensionality reduction based on principal components is the most used methodology. Our paper examines three heuristics, namely Kaiser’
Mohit Baliyan, Evgeny M. Mirkes
doaj +1 more source
Principal Fitted Components for Dimension Reduction in Regression
We provide a remedy for two concerns that have dogged the use of principal components in regression: (i) principal components are computed from the predictors alone and do not make apparent use of the response, and (ii) principal components are not ...
Cook, R. Dennis, Forzani, Liliana
core +2 more sources
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source