Results 71 to 80 of about 5,566,031 (259)

Robust sparse principal component analysis. [PDF]

open access: yes
A method for principal component analysis is proposed that is sparse and robust at the same time. The sparsity delivers principal components that have loadings on a small number of variables, making them easier to interpret.
Croux, Christophe   +2 more
core  

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Detecting Genotype-Population Interaction Effects by Ancestry Principal Components

open access: yesFrontiers in Genetics, 2020
Heterogeneity in the phenotypic mean and variance across populations is often observed for complex traits. One way to understand heterogeneous phenotypes lies in uncovering heterogeneity in genetic effects.
Chenglong Yu   +8 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

A principal components analysis of the UK term structure and the influence of fiscal policy [PDF]

open access: yes
This study examines the use of principal component techniques in analysing term structures of interest rates. It employs original methods of estimating B-Spline models with endogenous knot positions and applies the method of Dierckx (1981) to generate ...
Egginton, D. M. (Donald Michael)
core  

Principal components of nuclear mass model residuals

open access: yesPhysics Letters B
Principal Component Analysis (PCA) is applied to the residuals of six widely used nuclear mass models to uncover systematic deviations and identify missing physical effects in theoretical nuclear mass predictions. By analyzing the principal components of
Y. Y. Huang, X. H. Wu
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Principal Components and Factor Analysis. A Comparative Study. [PDF]

open access: yes
A comparison between Principal Component Analysis (PCA) and Factor Analysis (FA) is performed both theoretically and empirically for a random matrix X:(n x p) , where n is the number of observations and both coordinates may be very large.
Travaglini, Guido
core  

Using artificial intelligence in analyzing principal components

open access: yesSustainable Engineering and Innovation
In this research, the basic concepts of both principal component analysis and artificial neural networks were reviewed, let alone tackling breast cancer, its most important causes and early detection. To add more, obtaining the principal components of a
Hasanain Jalil Neamah Alsaedi
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

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