Results 121 to 130 of about 2,337,506 (337)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Permutation tests to estimate significances on Principal Components Analysis [PDF]

open access: yesComputational Ecology and Software, 2012
Principal Component Analysis is the most widely used multivariate technique to summarize information in a data collection with many variables. However, for it to be valid and useful the meaningful information must be retained and the noisy information ...
Vasco M. N. C. S. Vieira
doaj  

Principal Components and Factor Analysis. A Comparative Study. [PDF]

open access: yes
A comparison between Principal Component Analysis (PCA) and Factor Analysis (FA) is performed both theoretically and empirically for a random matrix X:(n x p) , where n is the number of observations and both coordinates may be very large.
Travaglini, Guido
core   +1 more source

An online algorithm for contrastive Principal Component Analysis [PDF]

open access: green, 2022
Siavash Golkar   +3 more
openalex   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Caracterização e Divergência Genética de Populações de Casearia grandiflora no Cerrado Piauiense

open access: yesFloresta e Ambiente
RESUMO Casearia grandiflora (Salicaceae) é uma espécie típica do cerrado piauiense, o conhecimento da diversidade genética dessa espécie é de grande importância para estabelecimento de práticas e estratégias de conservação biológica.
Marcones Ferreira Costa   +6 more
doaj   +1 more source

Growth Regressions, Principal Components and Frequentist Model Averaging [PDF]

open access: yes
This paper offers two innovations for empirical growth research. First, the paper discusses principal components augmented regressions to take into account all available information in well-behaved regressions.
Hlouskova, Jaroslava, Wagner, Martin
core  

Assessment of Pollution Stae of Beire Lake in Sri Lanka Using Water Quality Index, Trophic Status and Principal Component Analysis [PDF]

open access: green, 2023
Dilshi Dharmarathna   +4 more
openalex   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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