Results 121 to 130 of about 689,927 (311)

The Measurement of the Energy Intensity of Manufacturing Industries: A Principal Components Analysis [PDF]

Energy intensity is the ratio of energy use to output. Most industries deal with several energy sources and outputs. This leads to the usual difficulties of aggregating heterogeneous inputs and outputs.
Cote, Bruno, Bernard, Jean-Thomas
core  

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Mapping discourses through Hierarchical Clustering on Principal Components

Methodological Innovations
This article proposes a methodological framework that combines a Q-concourse questionnaire with Multiple Factor Analysis and Hierarchical Clustering on Principal Components (MFA/HCPC) to derive discourse typologies from large-N survey data. The framework
Francesco Veri
doaj   +1 more source

Incorporating Prior Knowledge of Principal Components in Genomic Prediction

Frontiers in Genetics, 2018
Genomic prediction using a large number of markers is challenging, due to the curse of dimensionality as well as multicollinearity arising from linkage disequilibrium between markers.
Sayed M. Hosseini-Vardanjani, Mohammad M. Shariati, Hossein Moradi Shahrebabak, Mojtaba Tahmoorespur   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

The importance of selecting the optimal number of principal components for fault detection using principal component analysis

, 2012
Includes summary.Includes bibliographical references.Fault detection and isolation are the two fundamental building blocks of process monitoring. Accurate and efficient process monitoring increases plant availability and utilization.
Khwambala, Patricia Helen
core  

Spatial and multivariate analysis of soybean productivity and soil physical-chemical attributes

Revista Brasileira de Engenharia Agrícola e Ambiental
The objective of this study was to evaluate the spatial variability of soybean yield, carbon stock, and soil physical attributes using multivariate and geostatistical techniques.
Ricardo N. Buss, Raimunda A. Silva, Glécio M. Siqueira, Jairo O. R. Leiva, Osmann C. C. Oliveira, Victor L. França   +5 more
doaj   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Estimating Coal Price Dynamics with the Principal Components Method [PDF]

The future use of coal depends on environmental protection measures and the Kyoto Protocol, the price of CO2 emission coupons, consumption, new technologies, the price of other energy sources and the liberalization of the electricity markets.
Volcjak, Robert, Repina, Sebastijan, Festic, Mejra   +2 more
core