Results 121 to 130 of about 2,367,896 (336)

Decomposing the Apoptosis Pathway Into Biologically Interpretable Principal Components

open access: yesCancer Informatics, 2018
Principal component analysis (PCA) is one of the most common techniques in the analysis of biological data sets, but applying PCA raises 2 challenges. First, one must determine the number of significant principal components (PCs). Second, because each PC
Min Wang   +2 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Caracterização e Divergência Genética de Populações de Casearia grandiflora no Cerrado Piauiense

open access: yesFloresta e Ambiente
RESUMO Casearia grandiflora (Salicaceae) é uma espécie típica do cerrado piauiense, o conhecimento da diversidade genética dessa espécie é de grande importância para estabelecimento de práticas e estratégias de conservação biológica.
Marcones Ferreira Costa   +6 more
doaj   +1 more source

Principal Components and Factor Analysis. A Comparative Study. [PDF]

open access: yes
A comparison between Principal Component Analysis (PCA) and Factor Analysis (FA) is performed both theoretically and empirically for a random matrix X:(n x p) , where n is the number of observations and both coordinates may be very large.
Travaglini, Guido
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Growth Regressions, Principal Components and Frequentist Model Averaging [PDF]

open access: yes
This paper offers two innovations for empirical growth research. First, the paper discusses principal components augmented regressions to take into account all available information in well-behaved regressions.
Hlouskova, Jaroslava, Wagner, Martin
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

THE ROLE OF CORPORATE ENTREPRENEURSHIP IN COMPETITIVENESS. DATA ANALYSIS OF QUANTITATIVE. PART 2

open access: yesContemporary Economy, 2016
The article presents conclusions regarding application of Principal Component Analysis to data about to measure the entrepreneurial potential of the company.
Aneta Oniszczuk-Jastrząbek
doaj  

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