Results 211 to 220 of about 689,927 (311)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Principal Components for Practice-Oriented Measurement of Running Technique: A Proof-Of-Concept Study. [PDF]

Eur J Sport Sci
Debertin D, Kiebacher J, Zhang M, Federolf P.   +3 more
europepmc   +1 more source

Competitive and Recreational Running Kinematics Examined Using Principal Components Analysis. [PDF]

Healthcare (Basel), 2021
Quan W, Zhou H, Xu D, Li S, Baker JS, Gu Y.   +5 more
europepmc   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

Molecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini, Maria Caterina Mione   +1 more
wiley   +1 more source

DAPCy: a Python package for the discriminant analysis of principal components method for population genetic analyses. [PDF]

Bioinform Adv
Correa Rojo A, Moris P, Meuwissen H, Monsieurs P, Valkenborg D.   +4 more
europepmc   +1 more source

Physiological and Somatic Principal Components Determining VO₂max in the Annual Training Cycle of Endurance Athletes. [PDF]

Int J Environ Res Public Health, 2022
Grzebisz-Zatońska N, Poprzęcki S, Stanula A, Sadowska-Krępa E, Gerasimuk D.   +4 more
europepmc   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

An analysis of pacing profiles in sprint kayak racing using functional principal components and hidden Markov models. [PDF]

PLoS One
Estreich H, Bullock N, Osborne M, Santos-Fernandez E, Wu PP.   +4 more
europepmc   +1 more source

Stepwise Covariance-Free Common Principal Components (CF-CPC) With an Application to Neuroscience. [PDF]

Front Neurosci, 2021
Riaz U, Razzaq FA, Hu S, Valdés-Sosa PA.   +3 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source