Results 211 to 220 of about 2,367,896 (336)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

DAPCy: a Python package for the discriminant analysis of principal components method for population genetic analyses. [PDF]

Bioinform Adv
Correa Rojo A, Moris P, Meuwissen H, Monsieurs P, Valkenborg D.   +4 more
europepmc   +1 more source

Physiological and Somatic Principal Components Determining VO₂max in the Annual Training Cycle of Endurance Athletes. [PDF]

Int J Environ Res Public Health, 2022
Grzebisz-Zatońska N, Poprzęcki S, Stanula A, Sadowska-Krępa E, Gerasimuk D.   +4 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Biometric assessment of White Fulani cattle in a semi intensive production system in Northern Cameroon using principal components analysis

, 2019
E.P.J Ngono, Félix Meutchieye, Y. Manjeli   +2 more
openalex   +2 more sources

An analysis of pacing profiles in sprint kayak racing using functional principal components and hidden Markov models. [PDF]

PLoS One
Estreich H, Bullock N, Osborne M, Santos-Fernandez E, Wu PP.   +4 more
europepmc   +1 more source

Stepwise Covariance-Free Common Principal Components (CF-CPC) With an Application to Neuroscience. [PDF]

Front Neurosci, 2021
Riaz U, Razzaq FA, Hu S, Valdés-Sosa PA.   +3 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Combined analysis of multiple linear regression and principal components for predicting performance indicators in broiler chickens under commercial conditions. [PDF]

Poult Sci
Freitas RC, Calderano AA, Oliveira CH, Neto MG, Genova JL.   +4 more
europepmc   +1 more source

Covariate-adjusted hybrid principal components analysis for region-referenced functional EEG data. [PDF]

Stat Interface, 2022
Scheffler AW, Dickinson A, DiStefano C, Jeste S, Şentürk D.   +4 more
europepmc   +1 more source