Results 121 to 130 of about 569,117 (264)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Riemannian Principal Component Analysis

open access: yesCoRR
This paper proposes an innovative extension of Principal Component Analysis (PCA) that transcends the traditional assumption of data lying in Euclidean space, enabling its application to data on Riemannian manifolds. The primary challenge addressed is the lack of vector space operations on such manifolds.
openaire   +2 more sources

Quasicyclic Principal Component Analysis

open access: yesCoRR
We present quasicyclic principal component analysis (QPCA), a generalization of principal component analysis (PCA), that determines an optimized basis for a dataset in terms of families of shift-orthogonal principal vectors. This is of particular interest when analyzing cyclostationary data, whose cyclic structure is not exploited by the standard PCA ...
Susanna E. Rumsey   +2 more
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

EXPLORATORY ANALYSIS OF REGIONALIZED VARIABLES WITH FUNCTIONAL METHODS ANÁLISIS EXPLORATORIO DE VARIABLES REGIONALIZADAS CON MÉTODOS FUNCIONALES

open access: yesRevista Colombiana de Estadística, 2007
It is shown how summary statistics of functional data and functional principal components analysis (FPCA) can be used to evaluate the stationarity assumption considered in modeling of regionalized variables.
Giraldo Ramón
doaj  

Covariate-adjusted hybrid principal components analysis for region-referenced functional EEG data. [PDF]

open access: yesStat Interface, 2022
Scheffler AW   +4 more
europepmc   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Online Principal Components Analysis [PDF]

open access: yesProceedings of the Twenty-Sixth Annual ACM-SIAM Symposium on Discrete Algorithms, 2014
Christos Boutsidis   +3 more
openaire   +1 more source

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