Results 101 to 110 of about 563,921 (264)
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
المجلة الدولية للأداء الاقتصادي, 2018 This work aims to apply principal components analysis and cluster analysis to determine the Agricultural capacities of Algeria. We find four agricultural areas. These areas characterized by the production of citrus fruits, potatoes and potatoes, cereals
Houssame Eddine BALOULI, Lazhar CHINE
doaj
Discover AgricultureGenetic divergence analysis assesses the level of genetic variation among different groups of organisms and quantifies differences between populations. This study aimed to assess the genetic diversity of traits, estimate genetic distance and cluster them
Birhan Kelemu, Yohannes Gedamu
doaj +1 more source
Federated Principal Component Analysis
, 2019 We present a federated, asynchronous, and $(\varepsilon, δ)$-differentially private algorithm for PCA in the memory-limited setting. Our algorithm incrementally computes local model updates using a streaming procedure and adaptively estimates its $r$ leading principal components when only $\mathcal{O}(dr)$ memory is available with $d$ being the ...
Grammenos, Andreas +3 more
openaire +3 more sources
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Ensemble Principal Component Analysis
IEEE Access20 pages, 8 ...
Olga Dorabiala +2 more
openaire +3 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
G3: Genes, Genomes, Genetics, 2016 We estimated local ancestry on the autosomes and X chromosome in a large US-based study of 12,793 Hispanic/Latino individuals using the RFMix method, and we compared different reference panels and approaches to local ancestry estimation on the X ...
Sharon R. Browning +8 more
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source