Results 81 to 90 of about 563,921 (264)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Attempt to define morphological parameters enabling sex determination of Ips typographus (Linaeus, 1758) (Coleoptera: Curculionidae: Scolytinae) using PCA and CLU

open access: yesJournal of Forest Science, 2014
There are only two known methods for determining the sex of Ips typographus (L.) - dissection that can­not be used with live beetles and by distinguishing between the density of the hairs on the head, a less reliable method that requires experienced ...
M. Zahradníková
doaj   +1 more source

A generalization of the principal component analysis

open access: yesJournal of the Japan Statistical Society, Japanese Issue, 1988
A nonlinear generalization of the principal component analysis (PCA) is made under normality. It is shown that this generalized PCA problem leads to an eigenvalue problem for the Hadamard products of the correlation matrix. In the framework of the generalized PCA, the result is applied to the problem of finding square-integrable continuous ...
Kariya Takeaki   +2 more
openaire   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Simultaneous Principal-Component Extraction with Application to Adaptive Blind Multiuser Detection

open access: yesEURASIP Journal on Advances in Signal Processing, 2002
SIPEX-G is a fast-converging, robust, gradient-based PCA algorithm that has been recently proposed by the authors. Its superior performance in synthetic and real data compared with its benchmark counterparts makes it a viable alternative in applications
Erdogmus Deniz   +3 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

LOCATION ATTRIBUTES OF EMERGING ECONOMIES: AN ANALYSIS USING PRINCIPAL COMPONENTS

open access: yesВісник Київського національного університету імені Тараса Шевченка. Серія Економіка, 2018
Our paper investigates the location attributes of a large sample of emerging economies from the perspective of foreign direct investments and multinational companies presence abroad.
L. Belascu, А. Horobet, O. Popovici
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

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