Results 61 to 70 of about 563,921 (264)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Tracing cattle breeds with principal components analysis ancestry informative SNPs. [PDF]
The recent release of the Bovine HapMap dataset represents the most detailed survey of bovine genetic diversity to date, providing an important resource for the design and development of livestock production. We studied this dataset, comprising more than
Jamey Lewis +5 more
doaj +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Angle Principal Component Analysis [PDF]
Recently, many ℓ1-norm based PCA methods have been developed for dimensionality reduction, but they do not explicitly consider the reconstruction error. Moreover, they do not take into account the relationship between reconstruction error and variance of projected data. This reduces the robustness of algorithms.
Qianqian Wang 0001 +3 more
openaire +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Principal components′ analysis of multifocal electroretinogram in retinitis pigmentosa
Aims : To determine waveforms of multifocal electroretinogram (mfERG) in patients with retinitis pigmentosa (RP) contributing significantly to the overall retinal response by using principal components′ analysis.
Aniruddha Maiti +4 more
doaj +1 more source
A Tutorial on Principal Component Analysis
Principal component analysis (PCA) is a mainstay of modern data analysis - a black box that is widely used but (sometimes) poorly understood. The goal of this paper is to dispel the magic behind this black box. This manuscript focuses on building a solid intuition for how and why principal component analysis works.
openaire +2 more sources
Binary Principal Component Analysis [PDF]
Efficient and compact representation of images is a fundamental problem in computer vision. Principal Component Analysis (PCA) has been widely used for image representation and has been successfully applied to many computer vision algorithms. In this paper, we propose a method that uses Haar-like binary box functions to span a subspace which ...
Feng Tang, Hai Tao
openaire +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Interpretation of the results of surface water quality applying multivariate analysis [PDF]
Monitoring of surface water, through the analysis of physical-chemical and chemical parameters is a very important factor in the control of water quality and the health of living beings. Surface water quality is largely determined by the nature (
Matijević Borko M. +4 more
doaj +1 more source

