Results 131 to 140 of about 2,229,496 (344)

Correlation and principal component analysis of clinical, bioelectrical and functional variables in newly diagnosed lung cancer adult patients. Pilot study [PDF]

open access: green, 2022
Justa Carmen Columbié Regüeiferos   +12 more
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

EXPLORATORY ANALYSIS OF REGIONALIZED VARIABLES WITH FUNCTIONAL METHODS ANÁLISIS EXPLORATORIO DE VARIABLES REGIONALIZADAS CON MÉTODOS FUNCIONALES

open access: yesRevista Colombiana de Estadística, 2007
It is shown how summary statistics of functional data and functional principal components analysis (FPCA) can be used to evaluate the stationarity assumption considered in modeling of regionalized variables.
Giraldo Ramón
doaj  

A Topological Principal Component Analysis.

open access: yes, 2020
Topological Principal Component Analysis (TPCA) is a multidimensional descriptive method witch studies a homogeneous set of continuous variables defined on the same set of individuals. Its a topological method of data analysis that consists of comparing and classifying proximity measures from among some of the most widely used measures for continuous ...
openaire   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

A principal components analysis of factors associated with successful implementation of an LVAD decision support tool. [PDF]

open access: yesBMC Med Inform Decis Mak, 2021
Kostick KM   +15 more
europepmc   +1 more source

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