Results 51 to 60 of about 95,004 (254)

Du spéculaire et du spéculatif dans l’(auto)portrait au féminin : le cas Thérèse mon amour de Julia Kristeva

open access: yesTrayectorias Humanas Trascontinentales, 2019
Dans Thérèse mon amour, Julia Kristeva nous propose une configuration énonciative et narrative qui interpelle notre réflexe habitué à la distinction nette des strates de l’énonciation.
Houcine Bouslahi
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Reduced leaflet stress in the stentless quadrileaflet mitral valve: a finite element model. [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND: Failure of bioprosthetics is usually caused by calcification of the leaflets as a consequence of high tensile stresses. The stentless valve resembles native mitral valve anatomy, has a flexible leaflet attachment and a suspension at the ...
Jian-Gang Wang   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

PCA Fault Feature Extraction in Complex Electric Power Systems

open access: yesAdvances in Electrical and Computer Engineering, 2010
Electric power system is one of the most complex artificial systems in the world. The complexity is determined by its characteristics about constitution, configuration, operation, organization, etc.
ZHANG, J., WANG, Z., ZHANG, Y., MA, J.
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Context modulation of facial emotion perception differed by individual difference. [PDF]

open access: yesPLoS ONE, 2012
BACKGROUND: Certain facial configurations are believed to be associated with distinct affective meanings (i.e. basic facial expressions), and such associations are common across cultures (i.e. universality of facial expressions).
Tae-Ho Lee   +2 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Towards quantifying (meta-)stability of multi-principal element alloys: from configurational entropy to characteristic temperatures

open access: yes, 2023
Abstract Understanding the thermodynamics of multi-principal-element alloys (MPEAs), although crucial for their design, remains an elusive task. The configurational entropy, Sconf, is a critical thermodynamic quantity determining stability, but its calculation for real materials poses a hard computational challenge. Strong of a highly efficient
Yanhui Zhang   +5 more
openaire   +1 more source

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