Results 61 to 70 of about 95,004 (254)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Research of plane symmetric antennas with the linear extending aperture for antenna grids

open access: yesФизика волновых процессов и радиотехнические системы, 2013
Mathematical models for plane symmetric antennas microwave range with linearly extending aperture, allowing to calculate their direction characteristics depending on an aperture configuration are received.
S.A. Parpula   +3 more
doaj  

Conclusive evidence of magnetic rotational band in 57Fe: Extending the shears mechanism to the fp shell orbital

open access: yesPhysics Letters B
A Magnetic Rotational (MR) band in 57Fe nucleus has been newly identified and established from the decreasing behaviour of the experimental electric dipole transition probabilities, B(M1), determined from the measured lifetimes of the states.
S. Basu   +34 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

L’accompagnement à l’orientation par les professeurs principaux de Terminale

open access: yesÉducation et Socialisation
This article uses the concept of mandate to examine the social conditions and the effectiveness of the expansion of the role of principal teachers in guidance.
Paul Lehner, Clément Pin
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Numerical Investigation of Aerodynamic Interactions in a Twin-Propeller Compound Helicopter

open access: yesAerospace
High-speed compound helicopters surpass the forward-speed limits of conventional helicopters and expand the flight envelope, yet close multi-component integration induces complex aerodynamic interference, whose underlying mechanisms and evolution with ...
Yutong Wang   +3 more
doaj   +1 more source

Predictive Analysis of the Principal Components that Configure Autistic Spectrum Disorder

open access: yesEuropean Journal of Theoretical and Applied Sciences
At currently, developments regarding to autism spectrum disorder have enabled its diagnostic group to be defined as a multilateral neurodevelopmental disorder characterised by peculiarities in the procedural functioning of perceptual-cognitive parameters, derived from a characteristic connexional form in the pathway of interconnection between intrinsic
openaire   +2 more sources

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