Results 81 to 90 of about 95,004 (254)

EFFICIENCY OF REDUNDANT SYSTEM THROUGH CONFIGURATION SUPERVISORS

Надежность и качество сложных систем, 2022
Background. The path to the creation of highly reliable equipment, each separate part of which, due to several factors, has limited reliability, is to develop reconfigurable systems with an excessive number of heterogeneous components. The objective of
А.М. Ageev, V.N. Bukov
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

INTER-RELAÇÃO ENTRE PAISAGEM, ORGANIZAÇÃO FLORÍSTICO-ESTRUTURAL EDEMOGRAFIA DO COMPONENTE ARBÓREO EM FLORESTA COM ARAUCÁRIAS

Ciência Florestal, 2018
The aim of this study was to investigate the interactions among the landscape spatial configuration, the floristic-structural organization and demographic rates of the tree component of a system of araucaria forest fragments, in Lages, Santa Catarina ...
Aline Pereira Cruz, Pedro Higuchi, Ana Carolina da Silva, Ricardo de Vargas Kilca, Juliana Pizutti Dallabrida, Karine Souza, Carla Luciane Lima, Vanessa Fátima Soboleski, Amanda da Silva Nunes, Rodineli Loebens   +9 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Effect of Ply Orientation and Face-Sheet Thickness on PSD-Based Random Vibration Response of Honeycomb Sandwich Structures

Designs
Electric vehicle battery enclosure systems under vibrational loading may experience structural damage, reducing the lifespan of lithium-ion cells. Honeycomb sandwich structures are widely used in EV battery systems due to their high stiffness-to-weight ...
Siddhanth Santhosh, Ananya Manjusha Raulkar, Pratham Gupta, Shah Mohammed Abdul Khader, Sathish Rao Udupi, Subash Acharya, Aruna Prabhu, Jonathan Monteiro, Divya Bhaskar, Ashwin Kumar Devaraj   +9 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Impact of Building Height and Window Configurations on Ventilation Performance and Temperature Distribution: A CFD Study of an Institutional Kitchen Environment

Journal of Daylighting
Institutional kitchens often experience inadequate thermal comfort and indoor air quality (IAQ) due to intense heat generation and pollutant emissions from cooking activities, increasing workers’ exposure to heat stress and related health risks ...
Jesna Mathew, Gnanasambandam Subbaiyan, Hareesh Krishnan H   +2 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Strength Characteristics of Unsaturated Compacted Loess Under Complex Stress Paths

Buildings
A series of (45 sets) true triaxial shear tests with controlled suction and under conditions of equal-b and equal-p are performed on unsaturated compacted loess.
Fang Zheng, Zhanping Song, Yuwei Zhang, Zhilang You   +3 more
doaj   +1 more source