Results 51 to 60 of about 260,594 (295)

Advances in martensitic transformations in Cu-based shape memory alloys achieved by in situ neutron and synchrotron X-ray diffraction methods [PDF]

, 2012
This article deals with the application of several X-ray and neutron diffraction methods to investigate the mechanics of a stress induced martensitic transformation in Cu-based shape memory alloy polycrystals. It puts experimental results obtained by two
Berveiller, Sophie, Malard, Benoît, Patoor, Etienne, Sittner, Petr   +3 more
core   +8 more sources

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

3D DEM simulation of hard rock fracture in deep tunnel excavation induced by changes in principal stress magnitude and orientation

Journal of Rock Mechanics and Geotechnical Engineering
To achieve the loading of the stress path of hard rock, the spherical discrete element model (DEM) and the new flexible membrane technology were utilized to realize the transient loading of three principal stresses with arbitrary magnitudes and ...
Weiqi Wang, Xia-Ting Feng, Qihu Wang, Rui Kong, Chengxiang Yang   +4 more
doaj   +1 more source

Comparative performance of some constitutive models in stress rotation

Open Geomechanics, 2021
The dilatancy/contractancy of soil is of particular importance for compaction, consolidation, liquefaction, etc. Interestingly, constitutive relations are often unsatisfactory in modelling volume changes in the sense that their predictions deviate ...
Fabian Schranz, Wolfgang Fellin, Dimitrios Kolymbas   +2 more
doaj   +1 more source

Experimental and numerical studies of ferritic stainless steel tubular cross sections under combined compression and bending [PDF]

, 2015
An experimental and numerical study of ferritic stainless steel tubular cross sections under combined loading is presented in this paper. Two square hollow section (SHS) sizes—SHS 40×40×240×40×2 and SHS 50×50×250×50×2 made of Grade EN 1.4509 (AISI 441 ...
Gardner, L, Rossi, B, Young, B, Zhao, O
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Earth Pressure on Retaining Wall with Surface-Inclined Cohesive Fill Based on Principal Stress Rotation

Geofluids, 2021
When considering the friction and bonding force between the back of the retaining wall and the horizontal fill behind the wall, the principal stress of the soil element near the vertical back of the retaining wall is no longer vertical and horizontal but
Hengli Wang, Zhengsheng Zou, Jian Liu, Xinyu Wang   +3 more
doaj   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Rotation of principal stress axes caused by faulting

Geophysical Research Letters, 1979
This note describes a simple procedure for determining the local rotation of principal stress axes caused by slip on a fault. The procedure employs Eshelby's solution for the elastic field of an ellipsoidal inclusion. An example is used to illustrate that this procedure may be useful in interpreting observations, such as the rotation of compression ...
openaire   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source