Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice
Advanced Healthcare Materials, EarlyView.A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec +5 more
wiley +1 more source
Entropy Bathtub for Living Systems: A Markovian Perspective. [PDF]
Entropy (Basel)Fornalski KW.
europepmc +1 more source
Controllable Dynamic Mechanical Cell Stimulation using Magnetically Actuated Artificial Cilia
Advanced Healthcare Materials, EarlyView.This paper introduces a platform based on magnetic artificial cilia for providing controllable dynamic mechanical stimulation to single cells, suitable for investigating large cell populations and enabling live cell imaging. Proof‐of‐principle experiments show that cell morphology is strongly influenced by the artificial cilia, that cellular forces can
Roel Kooi +5 more
wiley +1 more source
Information Content and Maximum Entropy of Compartmental Systems in Equilibrium. [PDF]
Entropy (Basel)Metzler H, Sierra CA.
europepmc +1 more source
Unveiling the Role of Curvature in Carbon for Improved Energy Release of Ammonium Perchlorate
Advanced Materials, EarlyView.High‐curvature carbon materials identified via machine learning and simulation can enhance the heat release and combustion performance of ammonium perchlorate. ABSTRACT The catalytic role of carbon curvature in the thermal decomposition of ammonium perchlorate (AP) remains largely unexplored. To address this gap, this study employs machine learning and
Dan Liu +8 more
wiley +1 more source
Lossless and Lossy Characterization of the State of Perturbed Anharmonic Diatomics: An Information-Theoretic Compaction of Quantum Dynamics. [PDF]
J Chem Theory ComputHamilton JR, Levine RD.
europepmc +1 more source
Advanced Materials, EarlyView.AI‐Assisted Workflow for (Scanning) Transmission Electron Microscopy: From Data Analysis Automation to Materials Knowledge Unveiling. Abstract (Scanning) transmission electron microscopy ((S)TEM) has significantly advanced materials science but faces challenges in correlating precise atomic structure information with the functional properties of ...
Marc Botifoll +19 more
wiley +1 more source
Quantifying Knowledge Production Efficiency with Thermodynamics: A Data-Driven Study of Scientific Concepts. [PDF]
Entropy (Basel)Chumachenko A, Buttliere B.
europepmc +1 more source
Advanced Materials, EarlyView.The Y supersaturation in the [Ba‐Cu(I/II)‐O] transient liquid composition is the driving force toward YBCO nucleation and growth in TLAG. Tuning the initial (Ba:Cu) molar ratio in the ink composition determines the YBCO epitaxial nucleation through supersaturation control.
Lavinia Saltarelli +12 more
wiley +1 more source
Number-Theoretic Methods in Statistics: Theory and Applications. [PDF]
Entropy (Basel)Fang KT, Zhou Y.
europepmc +1 more source