Results 111 to 116 of about 510 (116)

THE EFFECT OF PRINOMASTAT (AG3340), A POTENT INHIBITOR OF MATRIX METALLOPROTEINASE, ON A NEW ANIMAL MODEL OF EPIRETINAL MEMBRANE

Retina, 2004
To develop a simple epiretinal membrane (ERM) animal model and evaluate the efficacy of prinomastat (AG3340), a synthetic inhibitor of matrix metalloproteinase.This experiment was carried out on 18 eyes of nine Brown Norway rats. Preretinal hemorrhage was induced bilaterally using diode laser focused deeply on choroidal blood vessels.
Mohamed H, El-Bradey, Lingyun, Cheng, Dirk Uwe, Bartsch, Michael, Niessman, Abbas, El-Musharaf, William R, Freeman   +5 more
openaire   +2 more sources

Ventilator-induced lung injury upregulates and activates gelatinases and EMMPRIN: attenuation by the synthetic matrix metalloproteinase inhibitor, Prinomastat (AG3340).

American journal of respiratory cell and molecular biology, 2002
Mechanical ventilation has become an indispensable therapeutic modality for patients with respiratory failure. However, a serious potential complication of MV is the newly recognized ventilator-induced acute lung injury. There is strong evidence suggesting that matrix metalloproteinases (MMPs) play an important role in the development of acute lung ...
H D, Foda, E E, Rollo, M, Drews, C, Conner, K, Appelt, D R, Shalinsky, S, Zucker   +6 more
openaire   +1 more source

Prinomastat: combined with antineoplastics increases VTE

Reactions Weekly, 2003
openaire   +2 more sources

Metabolites of prinomastat and their synthesis

2003
OUELLETTE MICHAEL A, POTTS BARBARA CHRISTINE MUELLE, SRIRANGAM JAYARAM KASTURI, TIBBETTS ANTHONY RAYMOND, ZHANG KANYIN EDWARD   +4 more
openaire   +2 more sources

Prinomastat 192329‐42‐3

exaly  

Prinomastat: A Potent and Selective Matrix Metalloprotease Inhibitor–Preclinical and Clinical Development for Oncology

exaly