Results 181 to 190 of about 67,311 (287)

Human prion diseases [PDF]

, 2000
Matti Haltia
openalex   +1 more source

Mobile Powerhouses: Mitochondria Transfer via Tunnelling Nanotubes in Brain Health and Neurodegenerative Diseases

European Journal of Neuroscience, Volume 63, Issue 6, March 2026.
Within the brain microenvironment, mitochondria are preferentially transferred from glial cells to metabolically stressed neurons via tunnelling nanotubes (TNTs). This intercellular exchange restores bioenergetic homeostasis and contributes to mitochondrial quality control through transmitophagy.
Anna Henrich, Hannah Scheiblich
wiley   +1 more source

Overexpression of bank vole PrP(I109) in mice induces a spontaneous atypical prion disease with sex-dependent onset, early NfL elevation, and universal prion strain permissiveness. [PDF]

Acta Neuropathol Commun
Eraña H, Vidal E, Fernández-Borges N, Charco JM, Díaz-Domínguez CM, Sampedro-Torres-Quevedo C, San-Juan-Ansoleaga M, Fernández-Muñoz E, Galarza-Ahumada J, Pérez-Castro MÁ, Gonçalves-Anjo N, Piñeiro P, Pirisinu L, Di Bari MA, Giler S, Raimondi I, Espinosa JC, Vanni I, D'Agostino C, Rodríguez-Cuesta J, Pasetto L, Bonetto V, González-Martín N, Teijeira S, Zou WQ, Geijo M, Torres JM, Chiesa R, Sánchez-Martín MA, Nonno R, Requena JR, Castilla J.   +31 more
europepmc   +1 more source

Disulfide mapping reveals the domain swapping as the crucial process of the structural conversion of prion protein [PDF]

, 2011
Iva Hafner‐Bratkovič, Roman Jerala
openalex   +1 more source

Advancing prion diagnostics: full-length human E200K RT-QuIC substrate facilitates prion detection in tear fluid and improves sensitivity in cerebrospinal fluid. [PDF]

Acta Neuropathol Commun
Correia SDS, Schmitz M, Hermann P, Goebel S, Gerecke J, Lingor P, Maass F, Fischer AL, Canaslan S, Eraña H, Castilla J, Da Silva Correia A, Zerr I.   +12 more
europepmc   +1 more source

Pharmacological and genetic manipulation of autophagy and its impact on diverse prion infection scenarios

, 2011
Yasmine Aguib
openalex   +2 more sources

A fixed brain seeded amplification assay to complement neuropathological prion disease diagnosis. [PDF]

J Neuropathol Exp Neurol
Lewis V, Ellett L, Lei E, Stehmann C, Birchall I, Senesi M, McLean C, Collins SJ.   +7 more
europepmc   +1 more source

Backbone 1H, 13C, and 15N Chemical Shift Assignments for feline prion protein

, 2004
D.A. Lysek, Lucas G. Nivón, Kurt Wüthrich   +2 more
openalex   +1 more source

Co‐localization of tau and TDP‐43 after extracellular vesicle delivery to cells

The FEBS Journal, Volume 293, Issue 5, Page 1495-1515, March 2026.
Extracellular vesicles (EVs) derived from donor cells transfected with EGFP–2N4R‐tau or mCherry‐wtTDP‐43 were taken up by recipient cells, leading to cytosolic co‐localization of tau and TDP‐43. Molecular modeling revealed that tau and TDP‐43 directly interact through hydrogen bonding, suggesting a mechanistic link underlying their co‐pathology ...
Farhang Aliakbari, Kathryn Volkening, Zahra Nayeri, Aysegul Yucel Polat, Neil Donison, Jacqueline Palik, Michael J. Strong   +6 more
wiley   +1 more source

D178N prion protein mutation endows RML prions with new strain properties that do not mimic human genetic prion diseases. [PDF]

Acta Neuropathol
Masone A, Grasso A, Comerio L, Bruno R, Lavigna G, Vanni I, D'Agostino C, Orrù CD, Caughey B, Altmeppen HC, Castilla J, Giaccone G, Tagliavini F, Di Bari MA, Nonno R, Chiesa R.   +15 more
europepmc   +1 more source