Results 171 to 180 of about 69,500 (311)

Prion and Prion Diseases

, 2020
This review article provides the main information regarding a specific category of infectious diseases of animals and humans, the so-called transmissible spongiform encephalopathies, or prion infections. In a brief introduction explains the need for lighting issues in relation to environmental, veterinary public health importance in traffic and the ...
openaire   +1 more source

Production and Enzymatic Degradation of Sup35NM, a Prion-Like Protein from Yeast

, 2005
Prion diseases, or transmissible spongiform encephalopathies (TSEs), including human Creutzfeld-Jakob disease (CJD) and bovine spongiform encephalopathy (BSE), are fatal neurodegenerative diseases of humans and animals that are caused by aggregates of ...
Rojanatavorn, Kawan
core  

Automating creativity assessment in engineering design: A psychometric validation of AI‐generated items of the design problem task

Journal of Engineering Education, Volume 115, Issue 3, July 2026.
Abstract Background Creativity is essential for engineering design, yet its assessment remains challenging due to the resource‐intensive nature of traditional evaluation methods. Purpose/Hypothesis(es) This study investigates the potential of automatic item generation (AIG) using large language models (LLMs) to create psychometrically sound items for ...
Simone A. Luchini, Roger E. Beaty, Ayesha S. Boyce, Sarah E. Zappe, Boris Forthmann   +4 more
wiley   +1 more source

Prions, prions everywhere [PDF]

Nature Reviews Neuroscience, 2003
openaire   +1 more source

Harvest increase and culling as tools for managing chronic wasting disease in white‐tailed deer

The Journal of Wildlife Management, Volume 90, Issue 5, July 2026.
We used an agent‐based model to simulate the effect of CWD management on a white‐tailed deer population in northwest Indiana and northeast Illinois. Our results suggest that wildlife managers should reconsider how and if they should manage CWD. Abstract Chronic wasting disease (CWD), a transmissible spongiform encephalopathy that affects white‐tailed ...
Jonathan D. Brooks, Aniruddha V. Belsare, Joe N. Caudell, Patrick A. Zollner   +3 more
wiley   +1 more source

Strain-specific propagation of variant Creutzfeldt-Jakob disease prions in humanized neural cells. [PDF]

Proc Natl Acad Sci U S A
Rayner MLD, Arora P, Linehan JM, Ros H, Nihat A, Argentina F, Preston C, Schmidt C, Ribes JM, Klöhn PC, Mead S, Brandner S, Collinge J, Jat PS.   +13 more
europepmc   +1 more source

Fusion protein condensate formation via coiled‐coil domains

Protein Science, Volume 35, Issue 7, July 2026.
Abstract While recent research shows that biomolecular condensates play important roles in normal cellular processes and diseases, the driving forces in condensate formation are not well understood, especially regarding the role of structured self‐associative protein domains.
Om Prakash Narayan, Lu Liu, Kyle Scheller, Carter Humphrey, Jiawei Dong, Juan Guan   +5 more
wiley   +1 more source

Limited transmission of cervid prions to nonhuman primates provides insights into the zoonotic potential of chronic wasting disease. [PDF]

Sci Adv
Hannaoui S, Pritzkow S, Jürgens-Wemheuer WM, Motzkus D, Wälzlein JH, Schwenke KA, Cheng YC, Ahmed Hassan H, Zemlyankina I, Drever K, Beekes M, Schulz-Schaeffer WJ, Stahl-Hennig C, Gilch S, Soto C, Czub S, Schätzl HM.   +16 more
europepmc   +1 more source

The cellular prion protein and its role in Alzheimer disease

, 2009
The cellular prion protein (PrPC) is a membrane-bound glycoprotein especially abundant in the central nervous system (CNS). The scrapie prion protein (PrPSc, also termed prions) is responsible of transmissible spongiform encephalopathies (TSE), a ...
Cuadrado-Tejedor, M. (Mar), Irujo, A. (A.), Moleres, F.J. (Francisco J.), Velayos, J.L. (José Luis), Ferrer, V. (Vicente), Paternain, B. (B.)   +5 more
core  

PolyProline Predictor: A web server for empirical sequence‐based prediction of polyproline II helices

Protein Science, Volume 35, Issue 7, July 2026.
Abstract Polyproline II (PPII) helices are extended left‐handed secondary structures increasingly recognized for their roles in molecular recognition, signaling and within intrinsically disordered regions of proteins. Despite their functional importance, predicting regions with propensity to form PPII helices from sequence alone remains challenging due
Rubén López‐Sánchez, David Pantoja‐Uceda, Miguel Mompeán, Douglas V. Laurents   +3 more
wiley   +1 more source