Results 151 to 160 of about 69,500 (311)

Prions [PDF]

open access: yesCurrent Biology, 1999
openaire   +2 more sources

The Role of the Simulation in Supporting Newly Graduated Nurses in Their First 5 Months of Working Transition: Findings From a Mixed‐Method Study

open access: yesJournal of Clinical Nursing, EarlyView.
ABSTRACT Aims To understand the role of simulation in ensuring the development of the competencies expected by newly graduated register nurses (NGRNs) from the work initiation up to 5 months of transition. Methods Mixed‐method study design. A longitudinal phase employing the Nurse Competence Scale (NCS, from 0 to 100, excellent) to assess the perceived
Maura Mesaglio   +13 more
wiley   +1 more source

Chronic Wasting Disease Research in North America: A systematic review highlighting species-wise and interdisciplinary research trends

open access: yesPrion
Chronic Wasting Disease (CWD) research has experienced significant growth, spanning diverse disciplines such as genetics, immunology, modelling, and behaviour.
Chandika RG   +2 more
doaj   +1 more source

Bone Grafts: Everything You Need to Know

open access: yesJournal of Periodontal Research, EarlyView.
This review classifies bone grafts (autograft, allograft, xenograft, synthetic) by source and osteogenic/inductive/conductive potential, linking material properties and mechanisms to clinical indications in periodontal and dental regeneration. Key challenges—limited osteoinduction, poor vascularisation, unbalanced resorption, handling difficulties, and
Håvard Jostein Haugen   +5 more
wiley   +1 more source

Differential pathology of P102L-associated Gerstmann–Stäussler–Scheinker disease: exclusive presence of 8-kDa protease-resistant prion protein vs. co-existence of 8-kDa and type-1 protease-resistant prion protein, with a focus on codon 129 polymorphism

open access: yesPrion
Gerstmann – Sträussler – Scheinker disease (GSS) is a hereditary prion disease characterized by clinicopathological heterogeneity. In Japan, the most common mutation is P102L, typically associated with prion protein (PrP) plaques, spongiform changes, and
Hideko Noguchi   +12 more
doaj   +1 more source

Update on human prion disease

open access: yes, 2007
The recognition that variant Creutzfeldt–Jakob disease (vCJD) is caused by the same prion strain as bovine spongiform encephalopathy in cattle has dramatically highlighted the need for a precise understanding of the molecular biology of human prion ...
Wadsworth, Jonathan D.F., Collinge, John
core   +1 more source

Novel murine closed‐loop auditory stimulation paradigm elicits macrostructural sleep benefits in neurodegeneration

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Boosting slow‐wave activity (SWA) by modulating slow waves through closed‐loop auditory stimulation (CLAS) might provide a powerful non‐pharmacological tool to investigate the link between sleep and neurodegeneration. Here, we established mouse CLAS (mCLAS)‐mediated SWA enhancement and explored its effects on sleep deficits in neurodegeneration,
Inês Dias   +5 more
wiley   +1 more source

Specific early electroencephalogram for the diagnosis of sporadic Creutzfeldt-Jakob disease

open access: yesPrion
An early diagnosis is required for intervention in prion disease cases. To elucidate the specificity of early electroencephalography discharges in cases of sporadic Creutzfeldt-Jakob disease, we analysed epileptiform discharges through ...
Taiki Matsubayashi   +5 more
doaj   +1 more source

Six convincing reasons for cooperative TSE literature work

open access: yes, 2003
in: Proceedings Internationale Konferenz "Prion diseases - from basic research to intervention ...
Heynkes, R., Schütt-Abraham, I.
core  

The GSK3/SHAGGY‐like OsGSK3 phosphorylates and inhibits phase separation of OsFCA at Ser‐43 and Ser‐45 to regulate brassinosteroid signaling and rice architecture

open access: yesNew Phytologist, EarlyView.
A working model for GLYCOGEN SYNTHASE KINASE 3‐mediated phosphorylation of FLOWERING CONTROL LOCUS A in the regulation of brassinosteroid signaling and rice growth and development. Summary Brassinosteroid (BR) signaling plays a critical role in rice (Oryza sativa L.) grain development.
Jiaqi Zhang   +14 more
wiley   +1 more source

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