Results 131 to 140 of about 49,492 (243)

Limited transmission of cervid prions to nonhuman primates provides insights into the zoonotic potential of chronic wasting disease. [PDF]

Sci Adv
Hannaoui S, Pritzkow S, Jürgens-Wemheuer WM, Motzkus D, Wälzlein JH, Schwenke KA, Cheng YC, Ahmed Hassan H, Zemlyankina I, Drever K, Beekes M, Schulz-Schaeffer WJ, Stahl-Hennig C, Gilch S, Soto C, Czub S, Schätzl HM.   +16 more
europepmc   +1 more source

Reassessing the Proposed Creatine–PrP Axis in Endometriosis: Methodological and Mechanistic Considerations

Advanced Science, Volume 13, Issue 44, 7 August 2026.
ABSTRACT The research by Chen et al. (2024) presents an innovative hypothesis linking creatine metabolism to ferroptosis resistance in endometriotic stromal cells via PrP suppression. While conceptually valuable, methodological aspects warrant reflection.
Marco Machado
wiley   +1 more source

A Skull Bone Marrow‐to‐Brain Axis Links Osteoblastic Activity to Myeloid Cell Trafficking, Cerebral Blood Flow, and Cognition in Alzheimer's Progression

Advanced Science, Volume 13, Issue 43, 3 August 2026.
This study reveals that Alzheimer's disease–linked APP expression in bone‐forming cells drives skull bone marrow remodeling and alters its vascular connections to the brain. These changes disrupt immune cell trafficking, cerebral blood flow, and cognition. Targeting bone marrow macrophages restores brain function, highlighting a previously unrecognized
Lei Xiong, Dong Sun, Hao‐Han Guo, Daehoon Lee, Zhipeng Liu, Lin Mei, Wen‐Cheng Xiong   +6 more
wiley   +1 more source

Distinct prion conformers from brain and peripheral tissues of gene-targeted mice produce convergent CWD strain properties. [PDF]

PLoS Pathog
DeFranco JP, Atkinson ZN, Crowell J, Shi X, Kim S, Sun JL, Kane SJ, Telling GC.   +7 more
europepmc   +1 more source

Prion propagation is controlled by discrete structural regions of PrP rather than overall stability. [PDF]

J Biol Chem
Bhamra SK, Arora P, Liew M, Hosszu LLP, Batchelor M, Clarke AR, Bieschke J, Collinge J, Jat PS.   +8 more
europepmc   +1 more source

The power of many: when genetics met yeasts and high‐throughput

Biological Reviews, Volume 101, Issue 4, Page 1662-1682, August 2026.
ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley   +1 more source

Chemo-omic pipeline enables discovery of prion synaptotoxic pathways and inhibitory drugs. [PDF]

PLoS Pathog
Le NTT, Mercer RCC, Fang C, Sundaravadivelu A, Labadorf AT, Lin W, Kwan J, Blum B, Emili A, Harris DA.   +9 more
europepmc   +1 more source

Deep Mutational Scanning for the Study and Engineering of Protein Assemblies

Chemistry–Methods, Volume 6, Issue 8, August 2026.
This review explores how deep mutational scanning (DMS) can be used to improve understanding and accelerate engineering of protein assemblies, from natural fibers to engineered nanocages. We discuss various types of protein assemblies and their characterization, provide an introduction to the DMS technique, and then highlight examples in which DMS has ...
Jenna B. Wolfanger, Shoili Banerjee, Carolyn E. Mills   +2 more
wiley   +1 more source

Old nodes, new tricks: optimized methods for chronic wasting disease prion detection in preserved retropharyngeal lymph nodes. [PDF]

J Vet Diagn Invest
Munster A, Høy-Petersen J, Davis MA, Tomke SA, Niedringhaus KD, Gagne RB, Gibison M.   +6 more
europepmc   +1 more source

Prion Diseases [PDF]

Microbiology and Immunology, 1995
openaire   +3 more sources