Results 1 to 10 of about 2,266 (154)

RT-QuIC: a highly promising diagnostic method for neurodegenerative diseases-advantages and limitations. [PDF]

Front Neurol
Although it has been more than 200 years since Parkinson’s disease was described, we have not established biomarkers for its definitive diagnosis yet. Moreover, there is a similar case for the entire group of α-synucleinopathies, which are all characterized by the pathological accumulation of aggregated α-synuclein (α-Syn) in the brain and other ...
Koníčková D, Hraboš D, Menšíková K, Tučková L, Kaleta M, Strnad M, Colosimo C, Kaňovský P.   +7 more
europepmc   +6 more sources

Salivary α-Synuclein RT-QuIC Correlates with Disease Severity in de novo Parkinson's Disease. [PDF]

Mov Disord, 2023
Vivacqua G, Mason M, De Bartolo MI, Węgrzynowicz M, Calò L, Belvisi D, Suppa A, Fabbrini G, Berardelli A, Spillantini M.   +9 more
europepmc   +1 more source

Misfolded α-Synuclein Assessment in the Skin and CSF by RT-QuIC in Isolated REM Sleep Behavior Disorder. [PDF]

Neurology, 2023
Iranzo A, Mammana A, Muñoz-Lopetegi A, Dellavalle S, Mayà G, Rossi M, Serradell M, Baiardi S, Arqueros A, Quadalti C, Perissinotti A, Ruggeri E, Cano JS, Gaig C, Parchi P.   +14 more
europepmc   +1 more source

Identification of α-Synuclein Proaggregator: Rapid Synthesis and Streamlining RT-QuIC Assays in Parkinson's Disease. [PDF]

ACS Med Chem Lett, 2022
Takada F, Kasahara T, Otake K, Maru T, Miwa M, Muto K, Sasaki M, Hirozane Y, Yoshikawa M, Yamaguchi J.   +9 more
europepmc   +1 more source

Comparison of acetone and sodium phosphotungstic acid precipitation for sample enrichment prior to RT-QuIC for the detection of prion disease. [PDF]

BMC Res Notes
Nicholson EM, Veneziano SE.
europepmc   +1 more source

When Proteins Go MAD-Misfolded, Amplified, Detected: Advances in α-Synuclein Pathophysiology and RT-QuIC Detection. [PDF]

Mol Neurobiol
Labajová N, Polák A, Cehlár O, Križan P, Hritz J, Kolisek M, Škorvánek M, Škrabana R, Kovačech B, Žilka N.   +9 more
europepmc   +1 more source

Role of different recombinant PrP substrates in the diagnostic accuracy of the CSF RT-QuIC assay in Creutzfeldt-Jakob disease. [PDF]

Cell Tissue Res, 2023
Da Silva Correia SM, Schmitz M, Fischer A, Hermann P, Zerr I.   +4 more
europepmc   +1 more source

Biochemical signatures of skin α-synuclein in synucleinopathies revealed by RT-QuIC assay end-product analysis. [PDF]

Acta Neuropathol
Gerasimenko M, Yi H, Gilliland T, Chen Y, Wang Z, Zou WQ.   +5 more
europepmc   +1 more source

Diagnostic testing of chronic wasting disease in white-tailed deer (Odocoileus virginianus) by RT-QuIC using multiple tissues. [PDF]

PLoS One, 2022
Burgener KR, Lichtenberg SS, Lomax A, Storm DJ, Walsh DP, Pedersen JA.   +5 more
europepmc   +1 more source

RT-QuIC and Related Assays for Detecting and Quantifying Prion-like Pathological Seeds of α-Synuclein. [PDF]

Biomolecules, 2022
Srivastava A, Alam P, Caughey B.
europepmc   +1 more source