Results 81 to 90 of about 2,084,039 (283)
Bayesian methods in clinical trials: a Bayesian analysis of ECOG trials E1684 and E1690
BMC Medical Research Methodology, 2012 Background E1684 was the pivotal adjuvant melanoma trial for establishment of high-dose interferon (IFN) as effective therapy of high-risk melanoma patients. E1690 was an intriguing effort to corroborate E1684, and the differences between the outcomes of
Ibrahim Joseph G +2 more
doaj +1 more source
Ibn Al-Haitham Journal for Pure and Applied Sciences, 2020 In this paper, Bayesian estimator for the parameter and reliability function of inverse Rayleigh distribution (IRD) were obtained Under three types of loss function, namely, square error loss function (SELF), Modified Square error loss function ...
Masooma Ali Abod, Hazim Mansoor Gorgee
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
International Journal of Industrial Engineering and Production Research, 2014 The Weibull distribution has been widely used in survival and engineering reliability analysis. In life testing experiments is fairly common practice to terminate the experiment before all the items have failed, that means the data are censored.
fernando antonio Moala
doaj
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Prior Elicitation, Assessment and Inference with a Dirichlet Prior
Entropy, 2017 Methods are developed for eliciting a Dirichlet prior based upon stating bounds on the individual probabilities that hold with high prior probability. This approach to selecting a prior is applied to a contingency table problem where it is demonstrated ...
Michael Evans, Irwin Guttman, Peiying Li
doaj +1 more source
Prior Distribution and Model Confidence
CoRRWe study how the training data distribution affects confidence and performance in image classification models. We introduce Embedding Density, a model-agnostic framework that estimates prediction confidence by measuring the distance of test samples from the training distribution in embedding space, without requiring retraining. By filtering low-density
Maksim Kazanskii, Artem Kasianov
openaire +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
A cautionary note on using the scale prior for the parameter N of a binomial distribution [PDF]
, 2014 Statistical analysis of ecological data may require the estimation of the size of a population, or of the number of species with a certain population. This task frequently reduces to estimating the discrete parameter N representing the number of trials ...
Villa, Cristiano
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source