Results 71 to 80 of about 41,826 (310)
Biodiversity protection prioritisation: a 25-year review
There are insufficient resources available globally, nationally and in many regions, to conserve all species, habitats and ecosystems. Prioritisation of targets or actions is a rational response to resource scarcity.
Cullen, R
core +1 more source
Summary of the bariatric surgery prioritisation tool.
Summary of the bariatric surgery prioritisation tool.
Trisha O’Moore-Sullivan (10276421) +7 more
core +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Using String Distances for Test Case Prioritisation
International audienceTest case prioritisation aims at finding an ordering which enhances a certain property of an ordered test suite. Traditional techniques rely on the availability of code or a specification of the program under test. In this paper, we
Boroday, Sergiy +5 more
core +1 more source
BackgroundConcern about long waiting times for elective surgeries is not a recent phenomenon, but it has been heightened by the impact of the COVID-19 pandemic and its associated measures.
Dimuthu Rathnayake +2 more
doaj +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Prioritisation / query interface (screenshot).
This figure shows the query interface of GeneDistiller for the prioritisation example for epilepsy described in the text. The interface is divided into different sections in which the parameters describing a similar aspect of the gene-specific data are ...
Markus Schuelke (223245) +2 more
core +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
The Impact of Different Prioritisation Policies on Waiting Times: A Comparative Analysis of Norway and Scotland [PDF]
We compare the distributional consequences of two different waiting times initiatives. The primary focus of Scotland’s recent waiting time reforms has been on reducing maximum waiting times through the imposition of high profile national targets.
Askildsen, Jan Erik +4 more
core
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source

