Results 71 to 80 of about 9,338 (286)

Single‐Field Evolution Rule Governs the Dynamics of Representational Drift in Mouse Hippocampal Dorsal CA1 Region

open access: yesAdvanced Science, EarlyView.
Long‐term hippocampal place‐code dynamics are investigated using calcium imaging across weeks of maze navigation. Analyses reveal a novelty‐irrelevant Single‐Field Evolution Rule (SFER), where active fields promote persistence and inactive fields decline.
Cong Chen   +10 more
wiley   +1 more source

Comprehensive Profiling of N6‐methyladnosine (m6A) Readouts Reveals Novel m6A Readers That Regulate Human Embryonic Stem Cell Differentiation

open access: yesAdvanced Science, EarlyView.
This research deciphers the m6A transcriptome by profiling its sites and functional readout effects: from mRNA stability, translation to alternative splicing, across five different cell types. Machine learning model identifies novel m6A‐binding proteins DDX6 and FXR2 and novel m6A reader proteins FUBP3 and L1TD1.
Zhou Huang   +11 more
wiley   +1 more source

Reference‐Guided Chromosome‐by‐Chromosome de novo Assembly at Scale Using Low‐Coverage High‐Fidelity Long‐Reads with HiFiCCL

open access: yesAdvanced Science, EarlyView.
HiFiCCL, as the first assembly framework specifically designed for low‐coverage high‐fidelity reads, improves the assembly quality of existing assemblers and also enhances downstream applications such as large structural variant (SV) detection (>10 000 bp), synteny analysis, pangenome graph construction, and graph‐based individual‐specific germline SVs
Zhongjun Jiang   +9 more
wiley   +1 more source

Heuristic algorithms with rounded weights for a combinatorial food packing problem

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2017
In this paper, a lexicographic bi-criteria food packing problem arising in actual packaging equipments is considered. Given a set I = {i | i = 1,2,...,n} of current n items (for example, n green peppers) with their weights wi and priorities pi, the ...
Yoshiyuki KARUNO, Ryo SAITO
doaj   +1 more source

Quantitative Assessment of Randomized DNA Base Sequences Using Multi‐Model Physical Analysis for High‐Fidelity Data Storage

open access: yesAdvanced Science, EarlyView.
This study quantitatively evaluates randomized DNA sequence design for digital data storage using three physics‐based models. By applying encoding schemes with strict homopolymer constraints, the framework improves base randomness, GC balance, and error resilience. Experimental validation via PCR and Sanger sequencing confirms 95–98% decoding accuracy,
Seongjun Seo   +6 more
wiley   +1 more source

Priority-aware Radio Resource Scheduling for mMTC in 5G Networks - Balancing Efficiency and Fairness

open access: yesJournal of Telecommunications and Information Technology
Efficient and fair resource allocation for massive machine-type communication remains a significant challenge in 5G New Radio networks due to the diverse quality of service requirements and dynamic traffic patterns.
Prashant Kumar Baheti, Ajay Khunteta
doaj   +1 more source

Research on Task Priority Model and Algorithm for Satellite Scheduling Problem

open access: yesIEEE Access, 2019
In satellite scheduling system, one of the most important issues is task scheduling. Most of the existing algorithms focused on the scenario of normal tasks with fixed priority and don’t consider emergency tasks.
Jian Wu   +3 more
doaj   +1 more source

Inferring Gene Regulatory Networks From Single‐Cell RNA Sequencing Data by Dual‐Role Graph Contrastive Learning

open access: yesAdvanced Science, EarlyView.
RegGAIN is a novel and powerful deep learning framework for inferring gene regulatory networks (GRNs) from single‐cell RNA sequencing data. By integrating self‐supervised contrastive learning with dual‐role gene representations, it consistently outperforms existing methods in both accuracy and robustness.
Qiyuan Guan   +9 more
wiley   +1 more source

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