Results 101 to 110 of about 262,059 (354)
Priority Setting in the REACH System [PDF]
Toxicological Sciences, 2005 Due to the large number of chemicals for which toxicological and ecotoxicological information is lacking, priority setting for data acquisition is a major concern in chemicals regulation. In the current European system, two administrative priority-setting criteria are used, namely novelty (i.e., time of market introduction) and production volume.
Sven Ove, Hansson, Christina, Rudén
openaire +2 more sources
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Priority-setting assessment components.
The figure shows three main components of a priority-setting assessment: process, function, and outcome. In a basic form, a single process component leads to input for the function which produces an output as the final outcome of the priority-setting ...
Charlotte M. W. Gaasterland (18319804) +3 more
core +1 more source
A framework for priority-setting in climate smart agriculture research
Agricultural Systems, 2018 Climate-smart agriculture (CSA) is widely promoted as an approach for reorienting agricultural development under the realities of climate change. Prioritising research-for-development activities is crucial, given the need to utilise scarce resources as ...
P. Thornton +16 more
semanticscholar +1 more source
BMC Health Services Research, 2022 Background The COVID-19 pandemic actualised the dilemma of how to balance physicians´ obligation to treat patients and their own perceived risk of being infected.
Karin Isaksson Rø +4 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Trials, 2018 BackgroundDespite the problem of inadequate recruitment to randomised trials, there is little evidence to guide researchers on decisions about how people are effectively recruited to take part in trials.
P. Healy +22 more
semanticscholar +1 more source
Extending the Cooperative Phenotype: Assessing the Stability of Cooperation across Countries
Frontiers in Psychology, 2017 This paper studies whether individual cooperation is stable across settings and over time. Involving more than 7,000 subjects on two different continents, this study documents positive correlation in cooperative behavior across economic games in Norway ...
Amanda G. Reigstad +3 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Research priorities in gambling: Findings of a large-scale expert study [PDF]
ObjectiveWhile gambling is a growing public health concern, research resources are limited, and no guidance is available to prioritise research.
Stein, Dan J +31 more
core +1 more source