Results 81 to 90 of about 1,375,514 (306)

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Criteria and Framework for CGIAR Priority Setting [PDF]

, 1995
One of six papers submitted by TAC for discussion at ICW95 as part of the process of revising CGIAR priorities and strategies. This one discusses TAC's understanding of the guidelines laid out by the Group, highlights some themes for further attention ...
CGIAR Technical Advisory Committee
core  

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Setting Research Priority for Livestock Sector in Gujarat [PDF]

Research resource allocation strategy has been worked out for the livestock sector across districts/ regions of the Gujarat state by using multi-criteria scoring model. The study has covered all the 19 districts of the state and six livestock species. In
Das, N.C., Khunt, K.A.
core   +1 more source

Priority setting for research in health care: An application of value of information analysis to glycoprotein IIb/IIIa antagonists in non-ST elevation acute coronary syndrome [PDF]

, 2006
The purpose of this study is to explain the rationale for the value of information approach to priority setting for research and to describe the methods intuitively for those familiar with basic decision analytical modeling.
Bojke, L., Claxton, K., Palmer, S., Philips, Z., Sculpher, M.   +4 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Research priorities for young people with cancer: a UK priority setting partnership with the James Lind Alliance

BMJ Open, 2019
Objectives To conduct a UK-wide survey of young people who have experienced cancer, carers and professionals, to identify and prioritise research questions to inform decisions of research funders and support the case for research with this unique cancer ...
Faith Gibson, Rachael Hough, Lorna A Fern, Jeremy S Whelan, Susie Aldiss, Robert S Phillips, Amy Callaghan, Karen Dyker, Helen Gravestock, Michael Groszmann, Leila Hamrang, Demi McGeachy, Sue Morgan, Sam Smith, Sheela Upadhyaya, Helen Veitch, Lara Veitch, Max Williamson   +17 more
doaj   +1 more source

Public views on principles for health care priority setting: findings of a European cross-country study using Q methodology [PDF]

, 2015
International ...
Anand, Baker, Baker, Baker, Baker, Bobinac, Boot, Brouwer, Brouwer, Brown, Brown, Brown, Buljac, Buxton, Cam Donaldson, College voor Zorgverzekeringen, Cramm, Cuppen, Cuppen, Daniels, De Graaf, Dolan, Donabedian, Donaldson, Donaldson, Donaldson, Donaldson, Eccleston, Gagnon, Gerard, Goldberg, Greiner, Guttman, Helen Mason, Hofstede, Job van Exel, Klein, Kline, Kraijo, Lancsar, Linley, Litva, Lobo, Longson, McKeown, Menon, Mooney, National Institute for Health and Clinical Excellence, Nord, Pennington, Rachel Baker, Risdon, Robinson, Schmolck, Schwappach, Scottish Medicines Consortium NS, Smith, Stenner, Stephenson, Tielen, Tsuchiya, Van de Wetering, Van Eeten, Van Exel, Vermaire, Wallenburg, Watts, Weinstein, Werner Brouwer, Williams, Williams, Williams, Williams, Wiseman   +73 more
core   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

IDEAS project - Data Informed Platform for Health feasibility study in Uttar Pradesh [PDF]

, 2013
The IDEAS project sought to improve the health and survival of mothers and babies through generating evidence to inform policy and practice. This data collection contains topic guides and other research tools used to assess the feasibility of introducing
Bhattacharyya, Sanghita, Gautham, Meenakshi, Shrivastava, Aradhana   +2 more
core   +1 more source