Results 131 to 140 of about 262,059 (354)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Who and how should participate in health care priority setting? Evidence from a Portuguese survey [PDF]

This article provides highlights of the evolution of the health care rationing debate towards a more transparent and open approach involving public participation. Discretionary models that have dominated health sector decision-making are being questioned
Micaela M. Pinho, Paula Veiga, Anabela Botelho   +2 more
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Identifying and applying psychological theory to setting and achieving rehabilitation goals: development of a practice framework

, 2009
Goal setting is considered to be a fundamental part of rehabilitation; however, theories of behaviour change relevant to goal-setting practice have not been comprehensively reviewed.
Scobbie, Lesley, Dixon, D., Wyke, Sally, Dixon, Diane, Wyke, S., Scobbie, L.   +5 more
core   +1 more source

A note on the relative importance that people attach to different factors when setting priorities in health care [PDF]

, 2003
<i>Objective</i> To explore whether and to what extent people wish to give differential priority when asked to choose between providing health care treatment for different individuals or groups, on the basis of a range of factors, ranging ...
Dolan, P, Shaw, RL, Dolan, P., Dolan, Paul, Shaw, R., Shaw, Rebecca   +5 more
core   +1 more source

Priority setting for health in the context of devolution in Kenya: implications for health equity and community-based primary care

Health Policy and Planning, 2018
Devolution changes the locus of power within a country from central to sub-national levels. In 2013, Kenya devolved health and other services from central government to 47 new sub-national governments (known as counties).
Rosalind McCollum, S. Theobald, Lilian Otiso, T. Martineau, R. Karuga, E. Barasa, S. Molyneux, M. Taegtmeyer   +7 more
semanticscholar   +1 more source

Out-of-pocket expenditure and financial risks associated with treatment of chronic kidney disease in Ethiopia: a prospective cohort costing analysis

BMJ Global Health
Introduction In Ethiopia, most healthcare expenditures are paid out-of-pocket (OOP), while the burden of kidney disease (KD) is rapidly increasing, posing a major public health challenge in low- and middle-income countries, along with a staggering ...
Ole Frithjof Norheim, Solomon Tessema Memirie, Mizan Habtemichael, Hamelmal G Hailegiorgis, Leja Hamza Juhar, Tsegay Berhane, Sisay Tesfaye, Workagegnehu Hailu Bilchut, Maekel Belay Woldemariam, Lina Mohammed Ahmedtaha   +9 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Exploring the ethics of global health research priority-setting

BMC Medical Ethics, 2018
Thus far, little work in bioethics has specifically focused on global health research priority-setting. Yet features of global health research priority-setting raise ethical considerations and concerns related to health justice.
Bridget Pratt, M. Sheehan, N. Barsdorf, A. Hyder   +3 more
semanticscholar   +1 more source

The influence of identifiability and singularity in moral decision making

Judgment and Decision Making, 2015
There is an increased willingness to help identified individuals rather than non-identified, and the effect of identifiability is mainly present when a single individual rather than a group is presented.
Johanna Wiss, David Andersson, Paul Slovic, Daniel Västfjäl, Gustav Tinghög   +4 more
doaj   +1 more source