Results 51 to 60 of about 1,556,687 (280)

Pushing the Limits of Seagrass Remote Sensing in the Turbid Waters of Elkhorn Slough, California

Remote Sensing, 2019
Remote sensing imagery has been successfully used to map seagrass in clear waters, but here we evaluate the advantages and limitations of different remote sensing techniques to detect eelgrass in the tidal embayment of Elkhorn Slough, CA.
Heidi M. Dierssen, Kelley J. Bostrom, Adam Chlus, Kamille Hammerstrom, David R. Thompson, Zhongping Lee   +5 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Simulator scene display evaluation device [PDF]

, 1986
An apparatus for aligning and calibrating scene displays in an aircraft simulator has a base on which all of the instruments for the aligning and calibrating are mounted.
Haines, R. F.
core   +1 more source

Natamycin in the treatment of keratomycosis: Correlation of treatment outcome and in vitro susceptibility of fungal isolates

Indian Journal of Ophthalmology, 2011
In this study, 60 fungal isolates from 60 patients with fungal keratitis were tested in vitro for their susceptibility to natamycin and the mean minimum inhibitory concentrations of natamycin (MICn) were correlated with clinical outcome.
Linu Pradhan, Savitri Sharma, Suma Nalamada, Srikant K Sahu, Sujata Das, Prashant Garg   +5 more
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

On The Total Irregularity Strength of Regular Graphs

Journal of Mathematical and Fundamental Sciences, 2015
Let 𝐺 = (𝑉, 𝐸) be a graph. A total labeling 𝑓: 𝑉 ∪ 𝐸 → {1, 2, ⋯ , 𝑘} is called a totally irregular total 𝑘-labeling of 𝐺 if every two distinct vertices 𝑥 and 𝑦 in 𝑉 satisfy 𝑤𝑓(𝑥) ≠ 𝑤𝑓(𝑦) and every two distinct edges 𝑥1𝑥2 and 𝑦1𝑦2 in 𝐸 satisfy 𝑤𝑓(𝑥1𝑥2 ...
Rismawati Ramdani, A.N.M. Salman, Hilda Assiyatun   +2 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

PALS/PRISM Software Design Description (SDD): Ver. 0.51 [PDF]

, 2011
This Software Design Description (SDD) provides detailed information on the architecture and coding for the PRISM C++ library (version 0.51). The PRISM C++ library supports consistent information sharing and in- teractions between distributed components ...
Al-Nayeem, Abdullah, Kim, Cheolgi, Sha, Lui, Wu, Po-Liang, Yun, Heechul   +4 more
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source