Results 71 to 80 of about 1,574,901 (284)
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Retrospective analysis of the risk factors for developing phacomorphic glaucoma
Indian Journal of Ophthalmology, 2011 Aim : To determine the risk factors for developing phacomorphic glaucoma in eyes with mature cataracts. Materials and Methods : This is a case-control study comprising of 90 eyes with phacomorphic glaucoma and 90 age- and sex-matched control eyes with ...
Jacky W Y Lee +5 more
doaj +1 more source
Geospatial Validation and Topographic Map Revision of the Castner Glacier Area [PDF]
, 2012 Mapping in the interior of Alaska has always been a challenge due to the vast and remote aspects of the region. One contemporary method that has been used to map certain areas of the state has been the application of optical satellite data such as the ...
Cain, Grant
core
Structure factor and thermodynamics of rigid dendrimers in solution
, 2007 The ''polymer reference interaction site model'' (PRISM) integral equation theory is used to determine the structure factor of rigid dendrimers in solution.
Hansen J.-P. +6 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Thin lenses of asymmetric power
African Vision and Eye Health, 2009 It is generally supposed that thin systems, including refracting surfaces and thin lenses, have powers that are necessarily symmetric. In other words they have powers which can be represented assymmetric dioptric power matrices and in the familar ...
W. F. Harris, R. D. van Gool
doaj +1 more source
Social Networks through the Prism of Cognition
, 2018 Human relations are driven by social events - people interact, exchange information, share knowledge and emotions, or gather news from mass media. These events leave traces in human memory.
Kazienko, Przemysław +5 more
core +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Inverse Prism based on Temporal Discontinuity and Spatial Dispersion
, 2017 We introduce the concept of the inverse prism as the dual of the conventional prism and deduce from this duality an implementation of it based on temporal discontinuity and spatial dispersion provided by anisotropy.
Akbarzadeh, Alireza +2 more
core +1 more source