Results 81 to 90 of about 1,574,901 (284)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Accelerator system for the PRISM based muon to electron conversion experiment

, 2013
The next generation of lepton flavor violation experiments need high intensity and high quality muon beams. Production of such beams requires sending a short, high intensity proton pulse to the pion production target, capturing pions and collecting the ...
Alekou, A., Appleby, R., Aslaninejad, M., Barlow, R. J., Garland, J., Hock, R. Chudzinski K. M., Jenner, L. J., Kelliher, D. J., Kuno, Y., Kurup, A., Lagrange, J-B., Lancaster, M., Machida, S., Mori, Y., Muratori, B., Ohmori, C., Owen, H., Pasternak, J., Planche, T., Prior, C., Sato, A., Shi, Y., Smith, S., Uchida, Y., Witte, H., Yokoi, T.   +25 more
core  

Method for generating ultra-precise angles Patent [PDF]

, 1971
Optical device containing rotatable prism and reflecting mirror for generating precise ...
Appler, R. L.
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Enhancing the Spectral Sensitivity of Prism-Based SPR Sensors: The Role of Analyte RI

Chemosensors
A theoretical approach is presented to significantly enhance the spectral sensitivity of prism-based SPR sensors. The spectral sensitivity of prism-based SPR sensors is derived based on the coupling conditions of SPR and might exceed 105 nm/RIU for ...
Wenyuan Wang, Tianfa Liao, Hongxiang Lin, Han Cui, Xiaohui Wei   +4 more
doaj   +1 more source

Spectrum of visual impairment among urban female school students of Surat

Indian Journal of Ophthalmology, 2011
Aim : Eye morbidities with or without symptoms delineate a significant morbidity among adolescent schoolgirls in India. The study was undertaken to assess the extent of visual impairment and ocular morbidity to identify influencing factors and the impact
Mausumi Basu, Palash Das, Ranabir Pal, Sumit Kar, Vikas K Desai, Abhay Kavishwar   +5 more
doaj   +1 more source

Phase-conjugation of the isolated optical vortex using a flat surfaces

, 2014
The robust method for obtaining the helical interference pattern due to the phase-conjugation of an isolated optical vortex by means of the non-holographic technique is proposed.
A. Yu. Okulov, Allen, Arlt, Basistiy, Basov, Beth, Bhattacharya, Dennis, Felde, Hellwarth, Leach, Leach, MacDonald, Marchiano, Menachem, Nye, Okulov, Okulov, Okulov, Okulov, Okulov, Okulov, Puppe, Thiel, Veselago, Woerdemann, Zerrouki   +26 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Prevalence and Characteristics of Individuals with Preserved Ratio Impaired Spirometry (PRISm) and/or Impaired Lung Function in Japan: The OCEAN Study

International Journal of COPD, 2021
Toshihiko Kaise,1 Eishin Sakihara,2 Kentaro Tamaki,3 Hiroaki Miyata,4 Norimichi Hirahara,4 Oksana Kirichek,5 Ryosuke Tawara,1 Shoko Akiyama,1 Masayuki Katsumata,1 Mei Haruya,6 Takeo Ishii,7 Edgar P Simard,8 Bruce E Miller,8 Ruth Tal-Singer8 1Japan ...
Kaise T, Sakihara E, Tamaki K, Miyata H, Hirahara N, Kirichek O, Tawara R, Akiyama S, Katsumata M, Haruya M, Ishii T, Simard EP, Miller BE, Tal-Singer R   +13 more
doaj  

Bilateral macular holes in X-linked retinoschisis: Now the spectrum is wider

Indian Journal of Ophthalmology, 2011
Bilateral occurrence of macular hole in X-linked retinoschisis is an extremely rare event. Spectral domain optical coherence tomography (OCT) findings revealed that formation of a macular hole is secondary to the retinoschisis process alone.
Manoj Gautam, N S Muralidhar, Hemanth Murthy   +2 more
doaj   +1 more source