Results 81 to 90 of about 1,116,380 (291)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

cosmoss-jigu/prism: v1.0.1-asplos23-ae

open access: yes, 2023
This repository contains the source code for ACM ASPLOS 2023. Yongju Song, Wook-Hee Kim, Sumit Kumar Monga, Changwoo Min, and Young Ik Eom, "Prism: Optimizing Key-Value Store for Modern Heterogeneous Storage Devices," In Proceedings of the 28th ACM ...
Yongju Song
core   +1 more source

Bilateral macular holes in X-linked retinoschisis: Now the spectrum is wider

open access: yesIndian Journal of Ophthalmology, 2011
Bilateral occurrence of macular hole in X-linked retinoschisis is an extremely rare event. Spectral domain optical coherence tomography (OCT) findings revealed that formation of a macular hole is secondary to the retinoschisis process alone.
Manoj Gautam   +2 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Evaluating the reliability of NAND multiplexing with PRISM [PDF]

open access: yes, 2005
Probabilistic-model checking is a formal verification technique for analyzing the reliability and performance of systems exhibiting stochastic behavior.
Marta Kwiatkowska   +11 more
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Occult orbito-cranial penetrating injury by pencil: Role of beta tracer protein as a marker for cerebrospinal fluid leakage

open access: yesIndian Journal of Ophthalmology, 2011
Orbito-cranial foreign bodies present a treacherous situation that can escape detection. The only evidence of these foreign bodies may be the entry wound in the form of a small lid laceration.
Akash D Shah, Christian Decock
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

PRISM-Act framework.

open access: yes, 2023
IntroductionFoundational to a well-functioning health system is a strong routine health information system (RHIS) that informs decisions and actions at all levels of the health system.
Sarah Gimbel (324618)   +4 more
core   +1 more source

Ocular manifestations in the Hutchinson-Gilford progeria syndrome

open access: yesIndian Journal of Ophthalmology, 2011
The Hutchinson-Gilford progeria (HGP) syndrome is an extremely rare genetic condition characterized by an appearance of accelerated aging in children. The word progeria is derived from the Greek word progeros meaning ′prematurely old′. It is caused by de
Shivcharan L Chandravanshi   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy