Results 71 to 80 of about 178,592 (262)

L’éducation complexe sous le prisme de la philosophie du care [PDF]

Tréma, 2020
La convergence entre la pensée pragmatiste et les approches du care a été peu abordée dans le contexte francophone. C’est au prisme de la pensée complexe d’Edgar Morin que ce texte met en lumière les points de rencontre entre pragmatisme et philosophie du care.
openaire   +2 more sources

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

STAGES OF DEFORMATION OF THE UPPER NEOPROTEROZOIC COMPLEXES IN THE NORTHEAST OF THE CENTRAL TAIMYR TECTONOC ZONE

Геодинамика и тектонофизика
A study has been made of the morphological characteristics of the Upper Proterozoic rocks and their shear sense indicators in the island-arc complex of the northeastern Central Taimyr tectonic zone near the Main Taimyr fault.
K. S. Dodonov, A. K. Khudoley, V. F. Proskurnin, M. Yu. Kurapov, A. A. Bagaeva   +4 more
doaj   +1 more source

Electropositive metal complexes through the prism of the cyclopropyl group

, 2016
La thèse présente la chimie de complexes de métaux électropositifs portant le groupe cyclopropyle. La première partie du manuscrit décrit la synthèse et la caractérisation de dérivés du cyclopropyllithium ayant pour formule [1-R-c-C3H4Li] (R = SiMe3, Ph, SPh).
openaire   +2 more sources

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

Molecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis, Tereza Buchtová, Jirina Bartkova, Marie Lund Bay, Christoffer Lynge Halvorsen, Zuzana Machacova, Zdenek Skrott, Martin Mistrik, Ekaterina Dulina, Miguel Andujar‐Sanchez, Estrid Høgdall, Tine Henrichsen Schnack, Claus Høgdall, Berit Jul Mosgaard, Marie Boennelycke, Jacob Brink Laursen, Allan Jensen, Susanne K. Kjær, Tuula Kallunki, Robert Strauss, Jiri Bartek   +20 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

X-ray Crystal Structure, Geometric Isomerism, and Antimicrobial Activity of New Copper(II) Carboxylate Complexes with Imidazole Derivatives

Molecules, 2018
Five new copper(II) acrylate complexes (acr is the acrylate anion: C3H3O2) with imidazole derivatives (2-methylimidazole/2-MeIm, 5-methylimidazole/5-MeIm, 2-ethylimidazole/2-EtIm) of type: cis-[Cu(2-RIm)2(acr)2]·xH2O ((1): R = ⁻CH3, x = 2; (4):
Ioana Dorina Vlaicu, Gheorghe Borodi, Gina Vasile Scăețeanu, Mariana Carmen Chifiriuc, Luminița Măruțescu, Marcela Popa, Mariana Stefan, Ionel Florinel Mercioniu, Martin Maurer, Constantin G. Daniliuc, Rodica Olar, Mihaela Badea   +11 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

A Series of Lanthanide Coordination Polymers as Luminescent Sensors for Selective Detection of Inorganic Ions and Nitrobenzene

Molecules
Seven new lanthanide coordination polymers, namely [Ln(cpt)3H2O)]n(Ln = La (1), Pr (2), Sm (3), Eu (4), Gd (5), Dy (6), and Er (7)), which were synthesized under hydrothermal conditions using 4′-(4-(4-carboxyphenyloxy)phenyl)-4,2′:6′,4′-tripyridine (Hcpt)
Miao Wu, Juan Song, Yun-Long Zhou, Hui-Hui Chen, Bo-Feng Duan, Ling-Xia Jin, Chuan-Qing Ren, Jiu-Fu Lu   +7 more
doaj   +1 more source